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Cancer, Breast clinical trials

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NCT ID: NCT03167359 Completed - Inflammation Clinical Trials

Hypofractionated Radiotherapy in Breast Cancer

Start date: December 2010
Phase: N/A
Study type: Interventional

As the number of breast cancer (BrCA) survivors has markedly increased, clinicians are now seeking to reduce treatment-related toxicities and inconveniences of treatment, namely the traditional 6 weeks of daily radiation treatment (XRT). Skin thickening, fibrosis, and edema are some of the most common acute and potentially long-term debilitating toxicities of BrCA XRT. The purpose of this study is to learn if three weeks of daily radiation treatment (RT) to the breast is safe in breast cancer patients who are usually prescribed 6 weeks of daily radiation after breast surgery (e.g. lumpectomy or mastectomy) as standard of care.

NCT ID: NCT03164993 Completed - Clinical trials for Triple Negative Breast Cancer

Atezolizumab Combined With Immunogenic Chemotherapy in Patients With Metastatic Triple-negative Breast Cancer

ALICE
Start date: June 1, 2017
Phase: Phase 2
Study type: Interventional

This is a randomized, double-blind, placebo-controlled phase II study evaluating the safety and efficacy of Atezolizumab when combined with immunogenic chemotherapy in subjects with metastatic triple-negative breast cancer. Atezolizumab, pegylated liposomal doxorubicin and cyclophosphamide are the Investigational Medicinal Products (IMPs).

NCT ID: NCT02996201 Completed - Clinical trials for Chemotherapeutic Toxicity

Electronic Patient Reporting of Side Effects to Chemotherapy: A Cluster Randomized Controlled Trial

Start date: November 2015
Phase: N/A
Study type: Interventional

The aim of this study is to determine whether the use of breast cancer patients' own electronic reporting of side effects to chemotherapy in a treatment setting has an impact on the handling of side effects and on the number of hospitalizations, febrile neutropenia and dose adjustments. We are using the Patient-Reported Outcomes version of the Common Terminology Criteria for Adverse Events (PRO-CTCAE) for the patients' reporting of side effects.

NCT ID: NCT02958449 Completed - Cancer, Breast Clinical Trials

Prospective Clinical Investigation Comparing Standard Wound Closure Technique With Drains (Control) to Standard Wound Closure Techniques With TissuGlu® and No Drains (Test) in Mastectomy

Start date: December 2016
Phase: N/A
Study type: Interventional

Comparing standard wound closure technique with drains (control) to standard wound closure techniques with TissuGlu® and no drains (test) in mastectomy