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Caffeine clinical trials

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NCT ID: NCT06321861 Recruiting - Caffeine Clinical Trials

Motivational, Affective and Performance Effects of Caffeine Supplementation

Start date: January 19, 2024
Phase: N/A
Study type: Interventional

The main objective of the study is to evaluate the influence of caffeine intake on participants' energetic arousal, affect, motivation to achieve a training goal, satisfaction with training, and the sense of agency during training. Consequently, participants will engage in three sessions: caffeine, placebo, and no substance (in counterbalanced order). During each session, their affective and motivational states will be assessed, along with the performance of a standardized physical exercise test. The investigators hypothesize that participants who consume caffeine (caffeine condition) will exhibit higher levels of energy and motivation compared to the other two groups. Additionally, they are expected to experience greater optimism and expectancy regarding their training goals and achieve better results in the physical exercise test. A secondary aim of the study is to examine the impact of genetic variability on motivational and affective states of participants, as well as their performance in the physical exercise test after caffeine. The investigators will assess the CYP1A2 (-163C > A, rs762551; characterized such as "fast" (AA genotype) and "slow" caffeine metabolizers (C-carriers)) and ADORA2A (1976T > C; rs5751876; characterized by "high" (TT genotype) or "low" sensitivity to caffeine (C-carriers)).

NCT ID: NCT06210984 Not yet recruiting - Caffeine Clinical Trials

Caffeine and Training Intensity Quantification

Start date: January 31, 2024
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to learn about the effects of caffeine on exercise physiology and the subsequent quantification of athlete training zones in trained cyclists. The main questions that it aims to answer are: - What are the effects of low and moderate doses of caffeine on exercise physiology. - How do the effects of caffeine on exercise physiology affect the calculation of training zones. - Do the effects of caffeine on exercise physiology differ between men and women. Participants will complete four trials on a cycle ergometer as follows: - Trial 1: participants will complete two incremental tests to determine the power outputs required to elicit 50-80% of maximal oxygen consumption for trials 2-4. - Trials 2-4: participants will consume (in a randomized order) either a low (2 mg/kg) dose of caffeine, a moderate (5 mg/kg) dose of caffeine, or a placebo (maltodextrin), 45 minutes prior to to completing an incremental cycling test from 50-80% of maximal oxygen uptake. Measures of heart rate, oxygen uptake, blood lactate, and perceived exertion will be recorded throughout all trials. Researchers will compare the effects of exercise intensity, caffeine dose, and sex to see if they affect exercise physiology and training zone quantification.

NCT ID: NCT06195137 Completed - Caffeine Clinical Trials

Caffeine vs. ALA in BMS Treatment. (BMS: Burning Mouth Syndrome. ALA: Alpha-Lipoic Acid.)

Start date: December 13, 2021
Phase: N/A
Study type: Interventional

The aim of this study was to evaluate the efficacy of caffeine and alpha-lipoic acid in the treatment of burning mouth syndrome by symptom assessment with visual analogue scale.

NCT ID: NCT06079996 Completed - Caffeine Clinical Trials

Caffeinated Gum Softball Performance

Start date: May 20, 2022
Phase: N/A
Study type: Interventional

The purpose of this study was to investigate the effects of caffeinated chewing gum on female softball pitching and hitting performance. 24 trained female softball players (10 pitchers and 14 fielders) were divided into a caffeine chewing gum trial (CAF) or a placebo trial (PLA) in a single-blind, randomized, crossover experimental design. Two pieces of gum containing 100 mg of caffeine (CAF) or without caffeine (PLA) were chewed for 10 minutes and then spit out, followed by a 15-minute warm-up. The physical tests included grip strength and countermovement jump. The softball-specific tests included pitching (fast ball speed) or hitting (exit speed). The two trials were separated by seven days.

NCT ID: NCT06039358 Completed - Physical Activity Clinical Trials

Effects of Caffeine Ingestion on the Biomechanics of Healthy Young Subjects

Start date: October 6, 2023
Phase: N/A
Study type: Interventional

Caffeine is one of the few supplements that have enough scientific evidence to state that can notably improve performance, as different remarkable organizations in the sports nutrition context have classified it as an ergogenic aid with strong evidence regarding its efficacy and that is apparently safe. The beneficial effect of this substance on physical and cognitive performance has been identified in aerobic and anaerobic efforts, including aerobic and muscular endurance, power, or strength. However, it seems that the benefits of caffeine are usually measured only by its effect on performance, while a comprehensive analysis of its impact on other aspects of the movement technique of the exercise is not considered. Therefore, although caffeine generates better performance, a null or negative effect may occur on technique execution. As such, some consequences might arise (e.g., an increase in injury risk or a decrease in energy efficiency). The objective of this randomized controlled trial is to assess the influence of caffeine on certain biomechanical parameters of the technique of physical exercises in circumstances without fatigue and under neuromuscular fatigue. The study hypothesis is that caffeine generates modifications in the technical execution of certain movements in fatigued and unfatigued circumstances due to its physiological effects, which may be beneficial for performance and injury prevention. The participants will have to attend 5 sessions (enrollment, familiarization, control, placebo, and caffeine), at least 7 days apart. In the last 3 sessions, different measurements will be done to their technique while jumping, squatting, and running, without fatigue and with it. Other data will be collected throughout the study to contextualize and analyze in more detail the obtained information.

NCT ID: NCT06038903 Completed - Caffeine Clinical Trials

The Turkish Version Of The Brief-Caffeine Expectancy Questionnaire

Start date: September 8, 2023
Phase:
Study type: Observational [Patient Registry]

Caffeine is a psycho-active substance that is widely consumed in the world. It is seen that its widespread consumption is related to expectancies of consumption as well as cultural factors. Recreationally active individuals may have various expectations from caffeine consumption in line with their lifestyles and goals such as physical, social and/or other aspects. It can be stated that caffeine consumption expectancies have an important role in the process of evaluating consumption patterns. However, in the literature it seems to be very limited information about expectancies related to caffeine consumption. In this direction, the aim of the research was to test the compatibility of Brief-Caffeine Expectancy Questionnaire (B-CaffeQ) to Turkish culture and language. In the study, data will be collected from two separate participant groups and going to analysis. To reveal the structure on the first group (n=250-300 approx.) data, Exploratory Factor Analysis (EFA), and to verify the structure on the second group (n=313) data, Confirmatory Factor Analysis (CFA) will be used. Reliability will be assessed by performing test-retest and internal consistency analyzes on both the two data groups.

NCT ID: NCT06016985 Completed - Caffeine Clinical Trials

Effects of Caffeinated Gum on a Basketball-specific Tests in Basketball Players

Start date: July 1, 2023
Phase: N/A
Study type: Interventional

This study investigated the effects of chewing 3 mg/kg of caffeinated gum on basketball free throw accuracy and basketball -specific performance. Fifteen trained basketball players with at least a top 8 national ranking were recruited to be participants in this study. After 2 simulation tests to familiarize the experimental procedure, we employed a double blind, randomized crossover design to divide participants into caffeine trial (CAF) and placebo trial (PL). The CAF trial chewed caffeine gum containing 3 mg/kg for 10 minutes, whereas the PL trial chewed a placebo gum without caffeine. After 15 minutes rest, the stationary free throw shooting test, countermovement jump, t-test, 20-meter segmented dash test, squat in the flywheel device and running based anaerobic sprint test were conducted.

NCT ID: NCT05995314 Completed - Caffeine Clinical Trials

Effects Of Caffeine On Cognitive Performance

Start date: August 7, 2023
Phase: N/A
Study type: Interventional

Caffeine is a potent central nervous system stimulant that increases the activity in the prefrontal cortex and can improve cognitive skills. An improvement in these cognitive skills can lead to further benefits in athletic performance. Therefore, it is necessary to clarify the dose-response of caffeine on cognitive performance.The aim of this research will be to determine the effects of different doses of caffeine on sport-related cognitive aspects.

NCT ID: NCT05975489 Completed - Caffeine Clinical Trials

Genetics in the Effect of Caffeine on Fat Oxidation

Start date: October 1, 2020
Phase: N/A
Study type: Interventional

Genetic polymorphism on the effect of oral caffeine intake on fat oxidation during exercise has been studied in active and healthy population performing an incremental test on a cycle ergometer with 3-min stages at workloads from 30 to 70% of maximal oxygen uptake (VO2max). Participants performed this test after the ingestion of a) placebo; b) 3 mg/kg of caffeine; c) 6 mg/kg of caffeine. Fat oxidation rate during exercise was measured by indirect calorimetry. The influence of the CYP1A2 c.-163A>C, GSTP c.313A>G and PGC1a polymorphisms was evaluated to determine the effects on fat oxidation during exercise

NCT ID: NCT05916352 Completed - Caffeine Clinical Trials

Effects of Caffeine on Upper Extremity Performance

Start date: July 4, 2022
Phase: N/A
Study type: Interventional

It was aimed to apply caffeine supplement to elite basketball players and to investigate the effects of this supplement on upper extremity performance, lactic acid level and fatigue. The investigators also aimed to investigate the effects of blood lactate level on performance and fatigue.