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Caffeine Withdrawal clinical trials

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NCT ID: NCT06146517 Active, not recruiting - Anxiety Clinical Trials

A Single-Arm, Virtual Clinical Trial to Evaluate the Effects of a Sleep Supporting Beverage and Two Coffee Substitute Products

Start date: August 31, 2023
Phase: N/A
Study type: Interventional

This is a virtual, single-arm clinical trial that will last 12 weeks. Participants will trial three different products, each for 4 weeks. Participants will trial Clevr Blends Sleeptime during weeks 1-4, Clevr Matcha for weeks 5-8, and Clevr Blends Chai for weeks 9-12. Participants will complete questionnaires at Baseline and Week 2, 4, 6, 8, 10, and 12. In addition to data will be collected from participants' sleep tracking devices at Baseline, Week 2, and Week 4.

NCT ID: NCT06117280 Completed - Energy Clinical Trials

Effect of Different Dosages of Paraxanthine, the Major Caffeine Metabolite, on Energy and Focus

Start date: July 18, 2023
Phase: N/A
Study type: Interventional

Research has shown that acute ingestion of Paraxanthine (1,7-dimethylxanthine, PXN) can enhance various markers of focus, including memory, reaction time, and attention in healthy adults. To assess these effects, this placebo-controlled crossover trial will compare the effects of 200 and 300mg of PXN to a placebo control. Participants will abstain from caffeine for 3 days, before taking the first test/placebo product for 3 consecutive days. Participants will complete questionnaires at 30, 60, 90, and 120 minutes after ingestion on Day 1 and Day 3 of ingestion. Participants will have a 3-day washout period before trialing the next test product/placebo.

NCT ID: NCT05409339 Completed - Sleep Clinical Trials

Influence of Caffeine Consumption on the Human Circadian System

CICAFF
Start date: May 9, 2016
Phase: N/A
Study type: Interventional

Surveys indicate that 85% of the adult population consume caffeine on a daily basis. Caffeine acts on sleep homeostatic mechanisms by antagonizing the sleep factor adenosine. Whether and how caffeine also impacts on the circadian regulation of sleep and -wakefulness is fairly unexplored. This study quantifies the influence of regular caffeine intake and its cessation on circadian promotion of sleep and wakefulness, on circadian hormonal markers, well-being, neurobehavioral performance and associated cerebral mechanisms. The knowledge is expected to contribute important insights on recent societal changes in sleep-wake behavior (e.g., shorter sleep duration and delayed sleep phase) and the related increase in people suffering from sleep problems.

NCT ID: NCT05323578 Completed - Caffeine Clinical Trials

Consumption Status of Caffeine and Adverse Effects Experience Among Anesthetists

Start date: April 18, 2022
Phase:
Study type: Observational

High-caffeine consumption has been increasing in physicians, frequently causing the most common symptoms such as tremor, insomnia, anxiety, and nervousness and rarely leading to serious adverse effects like seizure, acute mania, and stroke due to caffeine overdose. There have been no studies regarding analysis of high-caffeine consumption and its adverse effects among anesthetists.

NCT ID: NCT05170464 Completed - Memory Deficits Clinical Trials

The Acute Effects of Exercise and Caffeine on Working Memory During Acute Caffeine Deprivation

Start date: January 10, 2022
Phase: Phase 2/Phase 3
Study type: Interventional

To determine the effects of moderate intensity exercise and caffeine on working memory in deprived caffeine consumers.

NCT ID: NCT04560595 Completed - Anxiety Clinical Trials

Remote Guided Caffeine Reduction

Start date: September 10, 2020
Phase: N/A
Study type: Interventional

The purpose of this online research study is to determine whether or not a gradual caffeine reduction program developed at Johns Hopkins can help people reduce their caffeine use. The investigators will provide materials to help guide caffeine reduction and ask questions to track caffeine use over several weeks. The investigators will also assess how reducing caffeine may benefit common caffeine-related problems such as anxiety, sleep disturbances, and gastrointestinal distress. The study will also determine whether or not people like participating in this caffeine reduction program in an online format.

NCT ID: NCT03022838 Terminated - Migraine Clinical Trials

The Effects of Caffeine Withdrawal on Migraine

Start date: February 28, 2017
Phase: Phase 2/Phase 3
Study type: Interventional

Sporadic and chronic dietary consumption of caffeine has substantial biological effects on the nervous system. The effects on migraine are at large not known. In this study we want to assess the effects of caffeine withdrawal on migraine.

NCT ID: NCT01376882 Completed - Cognitive Function Clinical Trials

Cognitive and Cerebral Blood Flow Effects of 2-week Caffeine Abstinence or Maintenance

Start date: March 2011
Phase: N/A
Study type: Interventional

The purpose of this study is to determine the effects of 2 weeks caffeine abstinence as compared to 2 weeks caffeine maintenance (300mg per day)on cognition and mood. Cerebral blood flow effects will also be assessed in a subset of participants. The role of caffeine abstinence/maintenance in the acute effects of caffeine will also be explored.