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Clinical Trial Details — Status: Not yet recruiting

Administrative data

NCT number NCT06173609
Other study ID # Long LIMA patch in CABG
Secondary ID
Status Not yet recruiting
Phase
First received
Last updated
Start date January 2024
Est. completion date December 2025

Study information

Verified date December 2023
Source Assiut University
Contact Marwan Ahmed Mohamed, resident doctor
Phone 01282636415
Email marwanahmed1997y2@gmail.com
Is FDA regulated No
Health authority
Study type Observational [Patient Registry]

Clinical Trial Summary

To assess the effect of LIMA patch as a method for the reconstruction on diffusely diseased LAD in the early and midterm outcomes


Description:

It is well-known that coronary artery bypass graft (CABG) surgery significantly increases life expectancy, so complete myocardial revascularization should be the main goal of the surgical intervention process (1). During coronary artery bypass surgery, the surgeon removes a piece of blood vessel from the leg, chest, arm, or belly. Then, the surgeon uses that piece of blood vessel (called a "graft") to reroute blood around the blocked artery. The surgery is called "bypass surgery" because it bypasses the blockage Complete revascularization in CABG is crucial to improve early and late outcomes after surgery. Conventional procedures cannot achieve satisfactory results in severely diseased left anterior descending coronary artery . Endarterectomy for severely atherosclerotic coronary artery disease (CAD) has a higher surgical risk and poor late outcomes . Reconstruction of diffusely diseased LAD with left internal mammary artery (LIMA) on-lay patch has less risk and complications than endarterectomy technique Ogus and colleagues used LIMA on-lay patches for the reconstruction of LAD based on the superior patency rate of the LIMA over other techniques which are more time-consuming. According to Lüscher and colleagues , the advantage of LIMA on-lay patch is to provide better vasomotor function and adjust the flow rate in proportion to the distal runoff. In the recent study by Rezk etal., reported that , LAD reconstruction with a LIMA patch could have a better short-term outcome than other techniques as saphenous vein patch without an endarterectomy for a diffusely diseased left anterior descending coronary artery.


Recruitment information / eligibility

Status Not yet recruiting
Enrollment 50
Est. completion date December 2025
Est. primary completion date January 2025
Accepts healthy volunteers
Gender All
Age group 30 Years to 90 Years
Eligibility Inclusion Criteria: - Any patient male,( or female) and his(or her) age from 30-90 years have Ischemic Heart Disease for CABG with diffusely diseased LAD. Exclusion Criteria: - Any patient performed open heart surgery before

Study Design


Related Conditions & MeSH terms


Intervention

Procedure:
CABG
During coronary artery bypass surgery, the surgeon removes a piece of blood vessel from the leg, chest, arm, or belly. Then, the surgeon uses that piece of blood vessel (called a "graft") to reroute blood around the blocked artery.

Locations

Country Name City State
n/a

Sponsors (1)

Lead Sponsor Collaborator
Assiut University

References & Publications (2)

Todorov IP, Todorova ZP, Nikolov DP. Angioplasty balloon occlusion of LIMA graft in reoperations of patients with prosthetic valve endocarditis and patent LIMA-LAD graft. Kardiochir Torakochirurgia Pol. 2022 Dec;19(4):199-204. doi: 10.5114/kitp.2022.122089. Epub 2022 Dec 24. — View Citation

Yang T, Yuan X, Li B, Zhao S, Sun H, Lu M. Long-term outcomes after coronary artery bypass graft with or without surgical ventricular reconstruction in patients with severe left ventricular dysfunction. J Thorac Dis. 2023 Apr 28;15(4):1627-1639. doi: 10.21037/jtd-22-1214. Epub 2023 Mar 23. — View Citation

Outcome

Type Measure Description Time frame Safety issue
Primary assess the effect of LIMA patch as a method for the reconstruction on diffusely diseased LAD in the early and midterm outcomes asses postoperative new arrhythmia//use of Inotropes// second session of surgery first week postoperative
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