Clinical Trials Logo

Clinical Trial Summary

To assess the effect of LIMA patch as a method for the reconstruction on diffusely diseased LAD in the early and midterm outcomes


Clinical Trial Description

It is well-known that coronary artery bypass graft (CABG) surgery significantly increases life expectancy, so complete myocardial revascularization should be the main goal of the surgical intervention process (1). During coronary artery bypass surgery, the surgeon removes a piece of blood vessel from the leg, chest, arm, or belly. Then, the surgeon uses that piece of blood vessel (called a "graft") to reroute blood around the blocked artery. The surgery is called "bypass surgery" because it bypasses the blockage Complete revascularization in CABG is crucial to improve early and late outcomes after surgery. Conventional procedures cannot achieve satisfactory results in severely diseased left anterior descending coronary artery . Endarterectomy for severely atherosclerotic coronary artery disease (CAD) has a higher surgical risk and poor late outcomes . Reconstruction of diffusely diseased LAD with left internal mammary artery (LIMA) on-lay patch has less risk and complications than endarterectomy technique Ogus and colleagues used LIMA on-lay patches for the reconstruction of LAD based on the superior patency rate of the LIMA over other techniques which are more time-consuming. According to Lüscher and colleagues , the advantage of LIMA on-lay patch is to provide better vasomotor function and adjust the flow rate in proportion to the distal runoff. In the recent study by Rezk etal., reported that , LAD reconstruction with a LIMA patch could have a better short-term outcome than other techniques as saphenous vein patch without an endarterectomy for a diffusely diseased left anterior descending coronary artery. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT06173609
Study type Observational [Patient Registry]
Source Assiut University
Contact Marwan Ahmed Mohamed, resident doctor
Phone 01282636415
Email marwanahmed1997y2@gmail.com
Status Not yet recruiting
Phase
Start date January 2024
Completion date December 2025

See also
  Status Clinical Trial Phase
Terminated NCT04459299 - CorPath GRX STEMI Study
Not yet recruiting NCT02853994 - Safety and Efficacy of the DEVOIR Sirolimus-Coated Coronary Balloon in the Real-world Clinical Practice N/A
Completed NCT02440893 - Understanding the Effect of Metformin on Corus CAD (or ASGES)
Completed NCT01486030 - Effect of Exercise Stress Testing on Peripheral Gene Expression Using Corus CAD (or ASGES) Diagnostic Test
Recruiting NCT06239493 - IVUS-Guided Treatment for Percutaneous Vascular Interventions
Recruiting NCT05344612 - Comparing a Diagnostic and Treatment Strategy of Upfront CTCA With SOC in Patients With Chest Pain and Suspected CAD N/A
Terminated NCT03901079 - Trial for A Novel Facilitated Antegrade Steering Technique in Revascularization of Coronary Chronic Total Occlusions
Completed NCT02457455 - Urgent Medical and Surgical Conditions During Flights N/A
Recruiting NCT05509010 - AI Driven National Platform for CT cOronary Angiography for clinicaL and industriaL applicatiOns Registry
Completed NCT03930589 - Remote Ischemic Conditioning in STEMI to Decrease Infarct Size N/A
Completed NCT01251302 - Utility of a Molecular Personalized Coronary Gene Expression Test (Corus CAD or ASGES) on Cardiology Practice Pattern
Withdrawn NCT02158754 - Clinician Utilization of Corus CAD (or ASGES) in Primary Care Provider Decision Making
Completed NCT01949844 - Artifact-Free High-Resolution Myocardial Perfusion MRI in Subjects With Abnormal Nuclear Myocardial Perfusion Studies N/A
Recruiting NCT04787796 - The Application of a Portable Multichannel ECG System for the Patients Suspected to Have Possible CAD or ACS N/A
Recruiting NCT03894423 - Comprehensive Computed Tomography Guidance of Coronary Bypass Graft Surgery
Completed NCT02223286 - Understanding Clinician Utilization of Corus CAD (Age/Sex/Gene Expression Score - ASGES) in Clinical Decision Making N/A
Recruiting NCT06154018 - Heparin Reversal With Two Different Protamine Ratios After Cardiopulmonary By-pass. N/A
Completed NCT02132611 - Coronary Orbital Atherectomy System Study N/A
Completed NCT01406990 - Aspirin Responsiveness in Women With Coronary Artery Disease N/A
Completed NCT01402804 - NSAIDs in Coronary Artery Disease Patients N/A