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Bypass Complication clinical trials

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NCT ID: NCT04930029 Not yet recruiting - Obesity Clinical Trials

Evaluation of Long-term Adverse Effects of Gastric Bypass in Omega

OMEGA10
Start date: September 2022
Phase:
Study type: Observational

The omega gastric bypass (OAGB) is developing worldwide as an alternative to the Y gastric bypass (RYGB). Cases of nutrition deficiency after OAGB, in particular protein deficency, are regularly reported in the literature, raising the question of the medium/long-term safety of this procedure. In its technology assessment report issued in September 2019 (HAS, 2019), the Haute Autorité de Santé rules on the invalidity of OAGB with a 200 cm biliary limb and the lack of sufficient data on the safety of OAGB with a 150 cm biliary limb compared to RYGB. The lack of long-term data on weight, resolution of comorbidities, quality of life, and endoscopic evaluation given the risk of lower esophageal cancer is also noted. The main objective of the study is to compare the incidence of serious adverse events related to surgery after OAGB at 10 years, according to 2 types of loop: a realization with a 150-cm biliary loop (OAGB AB150) versus a realization with a 200-cm biliary loop (OAGB AB200).

NCT ID: NCT04238923 Not yet recruiting - Vascular Diseases Clinical Trials

Topical Gentamicin and Vancomycin for Vascular Surgical Site Infection Prophylaxis

Start date: May 1, 2020
Phase: Phase 2/Phase 3
Study type: Interventional

Many patients who undergo vascular surgery to improve the blood flow to their legs are at risk of developing an infection in the surgical site and are then at risk of serious complications such as hospital readmission, failure of the surgical procedure and lower limb amputation. Surgical site infections may be reduced in high-risk patients by applying two commonly used antibiotics (gentamicin and vancomycin) into the surgical incision at the end of the surgical procedure. This will be compared to the standard of care treatment at London Health Sciences Center.

NCT ID: NCT04046861 Not yet recruiting - Cardiac Disease Clinical Trials

Influence of High Vitamin C Dose on Lactate During and After Extracorporeal Circulation

Start date: February 1, 2023
Phase: N/A
Study type: Interventional

The aim of our study is to find out whether high doses of vitamin C before cardiopulmonary bypass and during the first 24 hours after that have and impact of lowering the incidence of hyperlactatemia.