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Evaluation of Mitochondrial Dysfunction in Severe Burn and Trauma Patients

Trauma Clinical Trial

Official title:
Evaluation of Mitochondrial Dysfunction in Severe Burn and Trauma Patients

Clinical Trial Summary

The purpose of this project is to evaluate the level of mitochondrial dysfunction several patient populations: Burn, trauma, and control group of healthy volunteers. Study hypothesis: Increased plasma concentrations of a newly discovered inflammatory mediated, called mtDNA DAMPS associated with the occurrence of multi-organ dysfunction syndrome in severly injured patients. As the severity of a burn injury or trauma injury increase, so will systemic mitochondrial dysfunction.

Clinical Trial Description

Increased plasma concentrations of a newly discovered inflammatory mediated, called mtDNA DAMPS associated with the occurrence of multi-organ dysfunction syndrome in severly injured patients. A normal healthy sub-population will be used as a control. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01812941
Study type Interventional
Source University of South Alabama
Contact Jon Simmons, MD
Phone 251-471-7971
Email jdsimmons@health.southalabama.edu
Status Recruiting
Phase N/A
Start date September 2011
Completion date December 2021
View Details
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