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Burns clinical trials

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NCT ID: NCT05766917 Completed - Burns Clinical Trials

Peer Education on Core Health Outcomes Specific for Burn Patients

Start date: March 15, 2023
Phase: N/A
Study type: Interventional

Evaluate the Effectiveness of Peer Education on Core Health Outcomes Specific for Burn Patients

NCT ID: NCT05751174 Completed - Burns Clinical Trials

Determination of Nerve Growth Factor (NGF) Expression in Pediatric Patients With Severe Burns: a Pilot Study

Start date: March 18, 2021
Phase:
Study type: Observational

The goal of this observational study is to determine the blood values of NGF in severely burned patients, to describe any changes over time and finally to correlate the expression of NGF to the severity of the burn. The main question it aims to answer is: - describe NGF values in severely burned pediatric patients and to evaluate their correlation with the severity of the burn and the extent of the burned skin surface by measuring the circulating levels of NGF in pediatric patients. Participants will undergo blood sampling on days 2,7,14 and 30 after the traumatic event for the clinical follow-up envisaged by the internal protocol.

NCT ID: NCT05749003 Recruiting - Clinical trials for Lower Extremity Burns

Sensorimotor Training Exercise After Lower Extremity Burns

Start date: February 1, 2023
Phase: N/A
Study type: Interventional

Burn injury affects dermal tissue which contains sensory neurones that contribute to the conscious and automatic feedback systems which in turn, control balance and coordination. Impediments arising from lower limb burn injuries are similar to those observed in other populations suffering lower limb disease or pathology and further, these complications cause balance dysfunction. Balance and mobility are complex bodily functions integral to discharge disposition, social function and quality of life. Therefore, to guide recovery accurately and facilitate rehabilitation after LLBI, multi-factorial assessment is required.

NCT ID: NCT05729529 Recruiting - Clinical trials for Burning Mouth Syndrome

Impact of Alpha Lipoic Acid Efficacy in Burning Mouth Syndrome

Start date: January 20, 2020
Phase: N/A
Study type: Interventional

A double-blind placebo-controlled trial is conducted in order to evaluate the efficacy of alpha lipoic acid (ALA) and determine the statistical significance of the outcome variables. Burning mouth syndrome (BMS) is defined as an oral burning sensation in the absence of clinical signs which could justify the syndrome. Recent studies suggest the existence of neurological factors as a possible cause of the disease.

NCT ID: NCT05728450 Not yet recruiting - Burns Clinical Trials

Effect of Laser Puncture on Liver Enzymes Post Burn

Start date: February 19, 2023
Phase: N/A
Study type: Interventional

Procedures of laser puncture: - The treatment procedures will start after the patient's release from the intensive care unit. - The patient will be in a comfortable position. - The patient will wear protective eyeglasses. - The points for the application of laser acupuncture will be cleaned before application. All patients in the study group will be submitted to an infrared diode laser, wavelength 808 nm, Pulse duration: 200 ms, Power density: 0.4 W/cm2, energy density 4 J/cm2. - The plug of the laser unit will be inserted into the main current supply and the on/off switch will be switched on. The therapy form will be selected from the main menu and then the parameters will be set. - Acupuncture detector (Pointer Excel II) will be used for the definite location of acupuncture points. - Laser probe will be placed in contact with the skin perpendicular over the body acupoints Zusanli (ST36), Taichong (LR3), Tanyinjiao (SP6), Ganshu (BL18), Yan-glingquan (GB34) and Zhongwan (RN12) in both sides, with a duration of 90 sec for each point three times per week for a month.

NCT ID: NCT05728437 Not yet recruiting - Burns Clinical Trials

Effect of Resistance Exercises on Liver Enzymes Post Burn.

Start date: February 19, 2023
Phase: N/A
Study type: Interventional

Resistance training will be performed for 8 weeks with thrice-weekly sessions on non-consecutive days. The program will consist of seven exercises: triceps press, biceps curl, lat pull-down, calf raise, leg press, leg extension and sit-ups using dumbbells and sandbags. Each session will last approximately 45 minutes and consist of a 5-minute warm-up with stretching followed by a resistance exercise that will be done as a circuit, ending with a 5-minute cooldown. The 1 repetition maximum (1RM) is measured at baseline and following the intervention. Initially, participants will do two circuits using 50% of their 1RM and repeat them 10 times for the first and second weeks, progressing to two circuits, using 60% of their 1RM and repeating 10 times for the third and fourth weeks. In the fifth and sixth weeks, participants will do three circuits using 60% of their 1RM and repeat 10 times. In the last two weeks, patients will do three circuits using 70% of their 1RM and repeat 10 times. A 90-second rest will be allowed between sets of exercises (Hallsworth et al., 2011).

NCT ID: NCT05692557 Completed - Clinical trials for Acute Respiratory Distress Syndrome

Virtual Reality Distraction Technique to Improve Chest Burns With Acute Respiratory Distress Syndrome

Start date: September 1, 2020
Phase: N/A
Study type: Interventional

Inhalation of toxic gases and chemical irritants during the fire leads to damage to the respiratory tract or the alveolar tissue, which is known as smoke inhalation injury. Acute Respiratory Distress Syndrome (ARDS) is associated with smoke inhalation injury. These patients usually need physiotherapy in the form of chest mobilization and breathing exercises for up to 4 to 6 weeks after discharge from the burns care centre. The patients during this phase are usually in pain and extremely anxious about these exercises. Virtual reality distraction (VRD) is one such technique that is gaining immense popularity recently, it has more immersive distraction when compared to traditional distraction techniques. This study aims to investigate the effect of a virtual reality distraction (VRD) technique as a pain alleviation tool for reducing pain during physiotherapy in burns patients with acute respiratory distress syndrome (ARDS) in a hospital setting.

NCT ID: NCT05673551 Enrolling by invitation - Acute Pain Clinical Trials

VR-PAT During Home Burn Dressings - Multisite

Start date: January 16, 2023
Phase: N/A
Study type: Interventional

This study will evaluate the effectiveness of smartphone Virtual Reality Pain Alleviation Therapy (VR-PAT) as a pain distraction tool during repeated at-home burn dressing changes among 100 children (age 6-17 years) with a burn injury in comparison to 100 children with a burn injury who do not use the VR-PAT.

NCT ID: NCT05652816 Recruiting - Burn Degree Second Clinical Trials

Biological Skin Graft With Keratinocyte-stem Cell Co-cultre for Burn Patients

Start date: September 6, 2022
Phase: Early Phase 1
Study type: Interventional

The goal of this clinical trial is to test whether artificial skin graft can substitute autologous skin graft in current burn treatment. The main question it aims to answer is: • Can artificial skin graft result in better wound healing compared to the current burn treatment; autologous skin graft? You will: - Undergo debridement surgery - Receive artificial skin graft as an alternative to autologous skin graft - Undergo biopsy procedure of burn area If there is a comparison group: Researchers will compare autologous skin graft group to see the wound healing process

NCT ID: NCT05649891 Not yet recruiting - Pneumonia Clinical Trials

Checklists Resuscitation Emergency Department

Start date: September 2023
Phase: N/A
Study type: Interventional

The study will systematically evaluate how an emergency manual-a collection of checklists and fact sheets-affects the performance of resuscitation teams during the management of priority one patients in an emergency department.