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Clinical Trial Summary

This study will be a randomized, single-blind, prospective trial designed to evaluate the efficacy and safety of intra-arterial (IA) Verapamil diluted with normal saline compared to undiluted IA Nicardipine during transradial access (TRA) for percutaneous coronary angiography. Patients who are 18 years or older and undergoing non-emergent percutaneous coronary angiography via TRA will be included. Patients who are non-English speaking, pregnant, or intubated will be excluded. Patients will be randomized to one of the two following groups: 1. Group 1 will receive IA Verapamil 5 mg (2mL) diluted with 8 mL of normal saline 2. Group 2 will receive IA Nicardipine 400 mcg (undiluted, 8 mL) The investigators will document the patient's level of discomfort on the Visual Analogue Scale 30 seconds before and after administration of IA Verapamil/Nicardipine. The investigators will also document the presence of radial artery spasms.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT05625503
Study type Interventional
Source University of Illinois at Chicago
Contact Keshav R Patel, MD MS
Phone 734-306-3130
Email kpate447@uic.edu
Status Recruiting
Phase Early Phase 1
Start date December 13, 2022
Completion date December 1, 2023

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