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Observational Study of Insulin Resistance and Muscle Wasting After Burn Injury

Burn Clinical Trial

Official title:
Project 4: Molecular Mechanisms in Burn-induced Insulin Resistance in Humans

Clinical Trial Summary

The purpose of this study is to examine important and significant problems, that of insulin resistance and muscle wasting after burn injury.

Clinical Trial Description

Burn injury induces insulin resistance and our investigators have previous shown the importance of insulin receptor substrate 1 (IRS-1)-mediated pathways. This project will establish the inhibitory effects of burn injury on IRS-1 mediated signaling in human skeletal muscle of burn patients. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02029261
Study type Observational
Source Massachusetts General Hospital
Contact
Status Withdrawn
Phase
Start date May 2014
Completion date May 2018
View Details
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