Microneedling for Burn Hypertrophic Scars

Status Recruiting

Clinical Trial Summary

Approximately 33 to 91% of severe burn victims will develop hypertrophic scars. Hypertrophic scars are defined as erythematous (red), raised and rigid scars that can cause pain and itching, among other things. They cause psychological distress and affect the quality of life of burn victims. Microneedling is a technique that uses an electrical device to create hundreds of microchannels that penetrate the skin layers. This study is interested in determining the effectiveness of microneedling in improving the pliability, thickness and erythema of hypertrophic scars. Each scar will receive up to 5 ACS-pen treatments followed by the application of cortisone (triamcinolone acetonide). Knowing that microneedling increases the absorption of products applied to the skin by about 80%, it is logical to think that creating these channels to the dermis and applying cortisone afterwards would have a beneficial effect on the hypertrophic scars of these patients.

Clinical Trial Description

Patients will receive microneedling once every six weeks for a maximum of five treatments ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05423613
Study type	Interventional
Source	Centre hospitalier de l'Université de Montréal (CHUM)
Contact	Bernadette Nedelec
Phone	514-398-1275
Email	bernadette.nedelec@mcgill.ca
Status	Recruiting
Phase	N/A
Start date	January 22, 2021
Completion date	June 20, 2026

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT03664505` - Evaluation of the Product Properties of Individualized 3D-compression Garments to Treat Scars	N/A
Recruiting	`NCT05309720` - Dermal Substitution in Pediatric Burns	N/A
Not yet recruiting	`NCT04995302` - Microneedling Therapy With or Without Amnion Bilayer Sheeting on Scar Tissue	N/A
Not yet recruiting	`NCT04557514` - Comparative Study Between Fat Injection And Platelet Rich Plasma In Post Burn Facial Scar	N/A
Recruiting	`NCT05555602` - Observation of the Comfort and Efficacy of CO2 Laser Combined With Cryo 6 for Burn or Linear Scars.	N/A
Recruiting	`NCT05610878` - Efficacy of Preconditioned Adipose-Derived Stem Cells in Fat Grafting	Phase 1
Recruiting	`NCT01488240` - The Role of Pulsed Dye Laser Therapy in the Management of Burn Scars	N/A
Recruiting	`NCT01619917` - The Role of Fractional Vascular Laser Therapy in the Management of Burn Scars	N/A
Completed	`NCT03197649` - CO2 Laser Phototherapy for Management of Mature Burn Scars	N/A
Completed	`NCT04619589` - Characterization of Dyschromic Hypertrophic Scar
Completed	`NCT03627650` - Fat Grafting in Skin-grafted Deep Burn Scars	N/A
Completed	`NCT02417779` - Cutaneous Microcirculation After Extracorporeal Shock Wave Therapy	N/A
Completed	`NCT02417818` - Cutaneous Microcirculation After Plasma Therapy	N/A
Withdrawn	`NCT01075165` - Efficacy of Spray Silicone in Alteration of Burn Scar	N/A
Recruiting	`NCT04364217` - Pain and Itch Reduction in Burn Scars Treated With Fractional CO2 Laser	N/A
Completed	`NCT04412759` - PORCINE XENOGRAFT OR MICROBIAL CELLULOSE IN THE TREATMENT OF PARTIAL THICKNESS BURNS	N/A
Recruiting	`NCT06122090` - Treatment of Hypopigmented Scars With Bimatoprost	Phase 2
Active, not recruiting	`NCT04456127` - CO2 Laser Revision for Burn Related Donor Site Scars	N/A
Completed	`NCT03544697` - Easy Way of Choosing Rectangular Expander and Getting Maximum Benefit From Expanded Tissue
Terminated	`NCT01564407` - A Clinical Study of Allogeneic Human Dermal Fibroblasts for Remodeling Scar Contractures	Phase 1/Phase 2