Clinical Trials Logo

Clinical Trial Summary

Approximately 33 to 91% of severe burn victims will develop hypertrophic scars. Hypertrophic scars are defined as erythematous (red), raised and rigid scars that can cause pain and itching, among other things. They cause psychological distress and affect the quality of life of burn victims. Microneedling is a technique that uses an electrical device to create hundreds of microchannels that penetrate the skin layers. This study is interested in determining the effectiveness of microneedling in improving the pliability, thickness and erythema of hypertrophic scars. Each scar will receive up to 5 ACS-pen treatments followed by the application of cortisone (triamcinolone acetonide). Knowing that microneedling increases the absorption of products applied to the skin by about 80%, it is logical to think that creating these channels to the dermis and applying cortisone afterwards would have a beneficial effect on the hypertrophic scars of these patients.


Clinical Trial Description

Patients will receive microneedling once every six weeks for a maximum of five treatments ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05423613
Study type Interventional
Source Centre hospitalier de l'Université de Montréal (CHUM)
Contact Bernadette Nedelec
Phone 514-398-1275
Email bernadette.nedelec@mcgill.ca
Status Recruiting
Phase N/A
Start date January 22, 2021
Completion date June 20, 2026

See also
  Status Clinical Trial Phase
Completed NCT03664505 - Evaluation of the Product Properties of Individualized 3D-compression Garments to Treat Scars N/A
Recruiting NCT05309720 - Dermal Substitution in Pediatric Burns N/A
Not yet recruiting NCT04995302 - Microneedling Therapy With or Without Amnion Bilayer Sheeting on Scar Tissue N/A
Not yet recruiting NCT04557514 - Comparative Study Between Fat Injection And Platelet Rich Plasma In Post Burn Facial Scar N/A
Recruiting NCT05555602 - Observation of the Comfort and Efficacy of CO2 Laser Combined With Cryo 6 for Burn or Linear Scars. N/A
Recruiting NCT05610878 - Efficacy of Preconditioned Adipose-Derived Stem Cells in Fat Grafting Phase 1
Recruiting NCT01619917 - The Role of Fractional Vascular Laser Therapy in the Management of Burn Scars N/A
Recruiting NCT01488240 - The Role of Pulsed Dye Laser Therapy in the Management of Burn Scars N/A
Completed NCT03197649 - CO2 Laser Phototherapy for Management of Mature Burn Scars N/A
Completed NCT04619589 - Characterization of Dyschromic Hypertrophic Scar
Completed NCT03627650 - Fat Grafting in Skin-grafted Deep Burn Scars N/A
Completed NCT02417818 - Cutaneous Microcirculation After Plasma Therapy N/A
Completed NCT02417779 - Cutaneous Microcirculation After Extracorporeal Shock Wave Therapy N/A
Withdrawn NCT01075165 - Efficacy of Spray Silicone in Alteration of Burn Scar N/A
Recruiting NCT04364217 - Pain and Itch Reduction in Burn Scars Treated With Fractional CO2 Laser N/A
Completed NCT04412759 - PORCINE XENOGRAFT OR MICROBIAL CELLULOSE IN THE TREATMENT OF PARTIAL THICKNESS BURNS N/A
Recruiting NCT06122090 - Treatment of Hypopigmented Scars With Bimatoprost Phase 2
Active, not recruiting NCT04456127 - CO2 Laser Revision for Burn Related Donor Site Scars N/A
Completed NCT03544697 - Easy Way of Choosing Rectangular Expander and Getting Maximum Benefit From Expanded Tissue
Terminated NCT01564407 - A Clinical Study of Allogeneic Human Dermal Fibroblasts for Remodeling Scar Contractures Phase 1/Phase 2