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NCT01488240 Clinical Trial

The Role of Pulsed Dye Laser Therapy in the Management of Burn Scars

Burn Scar Clinical Trial

Official title:
The Role of Pulsed Dye Laser Therapy in the Management of Burn Scars

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT01488240
Other study ID # B2011: 074
Secondary ID
Status Recruiting
Phase N/A
First received
Last updated
Start date November 1, 2012
Est. completion date June 1, 2026

Study information
Verified date November 2023
Source University of Manitoba
Contact Justin P Gawaziuk, MSc
Phone 2047873669
Email jgawaziuk@hsc.mb.ca
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

The purpose of this study is to determine the effects (good or bad) of pulsed dye laser treatment in burn scar height, texture, redness and pliability in acute burn injury.

Description:

While the literature tends to support the use of laser therapy in the management of burn scars, there is a definite lack of appropriately powered, randomized controlled trials. Laser therapy can be quite expensive when compared to other treatment modalities for burn scars, and while promising, its true usefulness has yet to be conclusively demonstrated. For this reason, our research group is proposing the commencement of two randomized controlled trial pilot studies assessing the effects of pulsed dye laser (PDL) on burn scars. The objectives of this project will be to determine the effectiveness of pulsed dye laser therapy on burn scar vascularity, pliability, height and texture. It has been hypothesized that the PDL works on acute injury to decrease scar formation, and the fractional laser works on scar that is quiescent to promote remodelling. Therefore the investigators are proposing to study both acute injury and late burn scars. This project will compare the effects of each laser type, and will either help support or refute the assertion that laser therapy can be used to improve burn scars. Objectives: To determine the benefit of pulsed dye laser treatment in improving burn scar height, texture, vascularity and pliability in acute burn injury.

Recruitment information / eligibility
Status Recruiting
Enrollment 6
Est. completion date June 1, 2026
Est. primary completion date June 1, 2025
Accepts healthy volunteers No
Gender All
Age group 18 Years to 60 Years
Eligibility Inclusion Criteria: - burn scar - living in Winnipeg - scar age one to 6 months - Fitzpatrick I-III skin type Exclusion Criteria: - open wound - active infection - previous scar treatment with steroid injection or interferon - established disposition towards keloid scarring

Study Design

Related Conditions & MeSH terms

Intervention

Procedure:
• pulsed dye laser
laser energy

Locations
Country Name City State
Canada University of Manitoba Winnipeg Manitoba

Sponsors (1)
Lead Sponsor Collaborator
University of Manitoba

Country where clinical trial is conducted

Canada, 

Outcome
Type Measure Description Time frame Safety issue
Primary Scar Characteristics Examine characteristics of scar six months
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