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Burn Scar clinical trials

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NCT ID: NCT01619917 Recruiting - Burn Scar Clinical Trials

The Role of Fractional Vascular Laser Therapy in the Management of Burn Scars

Start date: November 1, 2012
Phase: N/A
Study type: Interventional

While the literature tends to support the use of laser therapy in the management of burn scars, there is a definite lack of appropriately powered, randomized controlled trials. Laser therapy can be quite expensive when compared to other treatment modalities for burn scars, and while promising, its true usefulness has yet to be conclusively demonstrated. For this reason, our assessing the effects of fractional vascular lasers on burn scars. It has been hypothesized that the fractional vascular lasers work on mature scars to decrease scar formation, and the fractional laser works on scar that is quiescent to promote remodelling. The retexturing/ resurfacing of the laser theoretically can decrease the visibility of the mesh pattern created by meshed split thickness skin graft). Objective: To determine the benefit of fractional vascular laser treatment in improving burn scar height, texture, vascularity and pliability in late burn scars.

NCT ID: NCT01564407 Terminated - Burn Scar Clinical Trials

A Clinical Study of Allogeneic Human Dermal Fibroblasts for Remodeling Scar Contractures

Start date: January 2011
Phase: Phase 1/Phase 2
Study type: Interventional

The primary objective of this study is to evaluate the safety of ICX-RHY-013 in the treatment of stable, restrictive scars in subjects who have suffered a burn injury. Evaluation will be achieved through regular assessment of adverse events, vital signs, blood work monitoring and laboratory analysis cellular properties of the scar through biopsy. The secondary objectives of this study are to evaluate improvement in symptoms of scars including reduced pain, discomfort and itching, improvement in mobility and daily function, improvement in appearance and scar texture.

NCT ID: NCT01488240 Recruiting - Burn Scar Clinical Trials

The Role of Pulsed Dye Laser Therapy in the Management of Burn Scars

Start date: November 1, 2012
Phase: N/A
Study type: Interventional

The purpose of this study is to determine the effects (good or bad) of pulsed dye laser treatment in burn scar height, texture, redness and pliability in acute burn injury.

NCT ID: NCT01075165 Withdrawn - Burn Scar Clinical Trials

Efficacy of Spray Silicone in Alteration of Burn Scar

Start date: March 2011
Phase: N/A
Study type: Interventional

In a burn population, conduct a prospective, double-blinded, randomized, controlled clinical trial to determine the ability of spray silicone to alter the physical characteristics of burn scar compared to a placebo.