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Burn Scar clinical trials

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NCT ID: NCT04772573 Completed - Burns Clinical Trials

The Treatment Challenges and Limitation in High-Voltage Pediatric Electrical Burn at Rural Area

Start date: August 7, 2017
Phase:
Study type: Observational

A case of high-voltage pediatric electrical burn involving a fully conscious 13-year old boy who was admitted to the emergency room after being electrocuted by high-voltage power cable, with superficial partial thickness burn over right arm, trunk, and left leg (26% of total body surface area) with cardiac abnormality e.g. tachycardia and non-specific ST depression. Treatments were based on Australian New Zealand Burns Association algorithm with several modifications, i.e. administering lower concentration of oxygen with nasal cannula instead of non-rebreathing mask and intravenous Ketorolac and Metamizole as analgesic instead of morphine due to limitation in infrastructure and knowledge. The patient underwent surgical debridement and strict observation with no signs of abnormality found during hospital stay. Wound dressing consisted of silver sulfadiazine, Sofra-tulle® and dry sterile gauze were used until epithelialization. After the wound healed, the patient resumed wearing elastic bandage and moisturizer on the wound area. The patient was observed daily through 7 days of hospitalization and followed-up for 1 year, achieving normal physiologic function of the affected area but unsatisfactory esthetic result. This case report showed that there is still a lack of burn prevention programs in the rural area, resulted in inadequate first aid application for electrical burn. There is a need for acknowledging and maximizing the implementation of available standardized guidelines e.g. Australian New Zealand Burns Association by giving homogenized training to personnel as well as providing feasible equipment, and then followed by strict monitoring for the patient. The focus of the burn program should also include burn rehabilitation, psychosocial needs and any complaints needing expert opinion in an outpatient setting in addition to adequate burn management for life saving and good wound healing.

NCT ID: NCT04619589 Completed - Hypertrophic Scar Clinical Trials

Characterization of Dyschromic Hypertrophic Scar

Start date: May 21, 2019
Phase:
Study type: Observational

Currently, there are limited prevention or treatments available for dyschromia in burn hypertrophic scars (HTSs). The limited available techniques involve transferring melanocytes from unaffected areas to the scar to adjust pigment. These techniques involve the creation of a donor site and do not utilize the cells that may already be present in scars. This study aims to confirm melanocyte presence in regions of hypo- and hyper- pigmented HTS. If melanocytes can be found in regions of hypopigmentation, these scars may be able to be treated in the future by pigmentation stimulators without the need for surgery. Additionally, if pigmentation specific molecules of interest can be found to be up-regulated in hyperpigmented scar, these may be able to be altered by a pharmacotherapy.

NCT ID: NCT04412759 Completed - Burns Clinical Trials

PORCINE XENOGRAFT OR MICROBIAL CELLULOSE IN THE TREATMENT OF PARTIAL THICKNESS BURNS

Start date: June 2016
Phase: N/A
Study type: Interventional

The purpose of this study was to compare two wound dressing products for partial thickness burns in adults.

NCT ID: NCT04340271 Completed - Burn Scar Clinical Trials

The Clinical Utility of Extracorporeal Shock Wave Therapy on Burns

Start date: April 15, 2020
Phase: N/A
Study type: Interventional

In burn patients, the wound healing process may lead to a fibrotic hypertrophic scar, which is raised, inflexible and responsible functional impairments. There are few studies which have investigated the effect of extracorporeal shock wave therapy (ESWT) on hypertrophic scar characteristics using objective measurements. Thus, this study aimed to ascertain the effects of ESWT on burn scars using objective measurements. This double-blinded, randomized, controlled trial involved 36 patients with burns. Patients were randomized into a ESWT (an energy flux density (EFD) of 0.05 to 0.30 mJ/mm2, frequency of 4Hz, and 1000 to 2000 impulses) or a sham stimulation group.

NCT ID: NCT04187586 Completed - Burn Scar Clinical Trials

Effect of Extracorporeal Shock Wave Therapy for Burn Scar Charateristics

Start date: December 10, 2019
Phase:
Study type: Observational

No study has investigated the effect of extracorporeal shock wave therapy (ESWT) on hypertrophic scar characteristics. Thus, this study aimed to ascertain the effects ESWT on burn scars. The investigators retrospectively reviewed burn patients who had undergone autologous split-thickness skin grafting (STSG) with same artificial dermis between January 2012 and September 2019.

NCT ID: NCT04176705 Completed - Burn Scar Clinical Trials

Fractional Ablative Laser Treatment for Skin Grafts

Start date: December 14, 2020
Phase: N/A
Study type: Interventional

Doctors and patients refer to all areas of skin changes from burn injury as burn scars. However, different areas of scars from burns can be treated differently. The burn scars that come from skin grafting surgery might be improved with laser treatment. The purpose of this study is to see if treating burn skin graft scars with a laser could make it better. Fractional Ablative Laser has been approved by the US Food and Drug Administration (FDA), but it has not been approved for use in the early stages of scar maturation and is considered investigational for this study.

NCT ID: NCT04157504 Completed - Burns Clinical Trials

Evaluation of Physical Functions in Lower Limb Burn Injury

Start date: January 10, 2018
Phase: N/A
Study type: Interventional

This study evaluates scar tissue, normal range of motion of lowr extremity joints, lower extremity functions, functional capacity, functional mobility, kinesiophobia and quality of life in lower limb burn injury.

NCT ID: NCT03664505 Completed - Burn Scar Clinical Trials

Evaluation of the Product Properties of Individualized 3D-compression Garments to Treat Scars

Start date: September 6, 2018
Phase: N/A
Study type: Interventional

Burn scars are treated with compression garments. These are produced based on manual measure data. The aim of this study is to evaluate correct fitting, wearing comfort, suitability for daily use and scar properties after using garments produced on base of measuring data from scanning in comparison to manual measured data.

NCT ID: NCT03627650 Completed - Burn Scar Clinical Trials

Fat Grafting in Skin-grafted Deep Burn Scars

Start date: May 1, 2013
Phase: N/A
Study type: Interventional

fat grafting in human skin-grafted immature burn scars histological, clinical and photographic follow-up

NCT ID: NCT03544697 Completed - Burn Scar Clinical Trials

Easy Way of Choosing Rectangular Expander and Getting Maximum Benefit From Expanded Tissue

Start date: January 2013
Phase:
Study type: Observational

Background: Tissue expanders are widely used for reconstruction of tissue defects. The choice of expander and planning the flap is complicated for the inexperienced surgeon. Objective: To demonstrate the choice of expander sizes proper for the tissue defect and maximum advancement technique during the defect coverage. Methods: The present study included 19 patients who were operated between January 2013 and January 2017. The expander projection was chosen in the manner that it would be more than the half length of the defect to be occurred and the expander width was chosen as wide as possible based on the area of its placement. After the expansion was completed, advancement method was used to cover the defect.