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NCT03435393 Clinical Trial

Ripple Mapping for Epicardial Mapping of Brugada Syndrome

Brugada Syndrome Clinical Trial

Official title:
Ripple-Mapping for the Detection of Long Duration Action Potential Areas in Patients With Brugada Syndrome

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT03435393
Other study ID # Barts_Brugada
Secondary ID
Status Recruiting
Phase N/A
First received February 9, 2018
Last updated February 15, 2018
Start date September 1, 2017
Est. completion date September 2020

Study information
Verified date February 2018
Source University College London Hospitals
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

Whether a mapping algorithm "Ripple-mapping" is able to rapidly identify the areas of long-duration multicomponent electrograms which constitute the targets for ablation for an automated strategy remains to be assessed.

Recruitment information / eligibility
Status Recruiting
Enrollment 10
Est. completion date September 2020
Est. primary completion date September 2019
Accepts healthy volunteers No
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria:

- Brugada syndrome patients requiring ablation

Exclusion Criteria:

- Patients not able to consent

Study Design

Related Conditions & MeSH terms

Intervention

Procedure:
• Catheter ablation
Mapping of the epicardium and ablating areas of long fractionated potentials

Locations
Country Name City State
Brazil Instituto do Coracao São Paulo
Portugal Hospital de Santa Cruz Lisbon
United Kingdom St Bartholomew's Hospital London

Sponsors (1)
Lead Sponsor Collaborator
University College London Hospitals

Countries where clinical trial is conducted

Brazil,  Portugal,  United Kingdom, 

Outcome
Type Measure Description Time frame Safety issue
Primary Eradication of Brugada syndrome pattern Disappearance of type 1 Brugada pattern on post-procedure ECG 24h post procedure
Secondary Freedom from ventricular arrhythmias No documentation of sustained ventricular tachycardia or ventricular fibrillation 12 months post-procedure
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