Worm Study: Modifier Genes in Sudden Cardiac Death

Status Recruiting

Clinical Trial Summary

Quest for modifier genes associated with ventricular arrhythmias in presence of a cardiac sodium channel gene (SCN5A-delPhe1617) mutation.

Clinical Trial Description

In a large Dutch SCN5A founder population with malignant ventricular arrhythmias, the investigators aim to identify genetic modifiers by means of whole-exome sequencing and to establish a comprehensive genotype-phenotype correlation, focussing on clinical and cellular electrophysiological characteristics and neurocardiac modulation. ;

Study Design

Allocation: Non-Randomized, Intervention Model: Parallel Assignment, Masking: Single Blind (Investigator), Primary Purpose: Diagnostic

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT02014961
Study type	Interventional
Source	Maastricht University Medical Center
Contact	Rachel ter Bekke, M.D.
Phone	+31433877098
Email	rachel.ter.bekke@mumc.nl
Status	Recruiting
Phase	N/A
Start date	April 2015
Completion date	April 2025

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