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Bronchoscopy clinical trials

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NCT ID: NCT03406546 Terminated - Sedation Clinical Trials

Sedation Strategies for Therapeutic Bronchoscopy

Start date: February 1, 2018
Phase: N/A
Study type: Interventional

Therapeutic bronchoscopy is a common procedure to treat respiratory diseases. The procedure includes stent implantation, bronchus dilation, electronic incision, laser therapy, and so on. Most of these procedures are painful and require general anesthesia. Conventionally, the general anesthesia for therapeutic bronchoscopy was performed using laryngeal mask. But in the previous experiences, the investigators found that sedation with dexmedetomidine and remifentanil was as effect as laryngeal mask anesthesia. The present study was performed to compare the two approach for sedation or anesthesia in therapeutic bronchoscopy.

NCT ID: NCT03406533 Terminated - Sedation Clinical Trials

Sedation Strategies for Diagnostic Bronchoscopy

Start date: February 1, 2018
Phase: N/A
Study type: Interventional

Diagnostic bronchoscopy is an invasive procedure performed to diagnose respiratory diseases. But pain has been complained by most of the patients receiving such procedures. Sedation or anesthesia was required by both of the patients and bronchoscopists. Unfortunately, no consensus has been made upon the sedation strategies. Multiple sedation approaches have been applied, such as midazolam and fentanyl, remifentanil and propofol, dexmedetomidine and propofol. The present study was designed to compare these protocols in sedation for diagnostic bronchoscopy.

NCT ID: NCT03294213 Completed - Anesthesia Clinical Trials

Prospective Non-interventional Evaluation of Intubation and Intensive Care Use of the New aScope™ 4 Broncho and aView

Start date: September 25, 2017
Phase:
Study type: Observational

This study is designed as a prospective observational, non-controlled, non-interventional study. The aim of this study is to obtain a broad user perspective of the aScope™ 4 Broncho, focusing on the device functionalities within regular clinical practice and therapeutic use of flexible bronchoscopes in the OR and ICU. The study will include a minimum of 100 adult patients admitted to the operating room (OR) or Intensive Care Unit (ICU) undergoing at least one bronchoscopy procedure. The inclusion will stop when 100 fully evaluable patients or a maximum of 150 patients have been enrolled. The involved sites will include patients during a five months' period, from September 2017 to January 2018.

NCT ID: NCT03086408 Completed - Bronchoscopy Clinical Trials

Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) and Diagnostic Bronchoscopy

Start date: May 9, 2017
Phase: N/A
Study type: Interventional

The purpose of this study is to investigate whether diagnostic bronchoscopy can be safely and potentially more effectively performed without the use of tracheal intubation or a supraglottic airway, under completely unobstructed surgical conditions afforded by THRIVE: Transnasal Humidified Rapid- Insufflation Ventilatory Exchange. THRIVE provides patient's gas exchange through rapid insufflation of high-flow oxygen via specialized nasal cannula.

NCT ID: NCT02296892 Completed - Bronchoscopy Clinical Trials

A Phase III Study of Remimazolam in Patients Undergoing Bronchoscopy

Start date: April 2015
Phase: Phase 3
Study type: Interventional

A prospective, double-blind, randomized, placebo and active controlled, multi-center, parallel group study comparing remimazolam to placebo, with an additional open label arm for midazolam, in patients undergoing a bronchoscopy.

NCT ID: NCT02289586 Recruiting - Clinical trials for Central Airway Stenosis

Interventional Bronchoscopy Under Noninvasive Ventilation

Start date: July 2014
Phase: N/A
Study type: Interventional

To evaluate the effect and safety of noninvasive ventilation assisted interventional bronchoscopy for hypoxemia patients with central airway stenosis. With the sedation and analgesia, noninvasive ventilation assisted interventional bronchoscopy for hypoxemia patients with central airway stenosis is safe and effective, carries high satisfaction rate.

NCT ID: NCT02268162 Recruiting - Lung Neoplasms Clinical Trials

Diagnosis of Individuals With Pulmonary Nodules by Different Bronchoscopy Combination

Start date: April 2015
Phase: N/A
Study type: Interventional

This study evaluates the value of different bronchoscopy combination for diagnosing peripheral pulmonary lesions suspected to be cancer. One-third of participants will receive routine bronchoscopy, while one-third of participants will receive bronchoscopy combined with a guiding equipment and the other one-third of participants will receive bronchoscopy combined with two or more guiding equipments. These guiding equipments include virtual bronchoscopic navigation(VBN), endobronchial ultrasonography with a guide sheath(EBUS-GS) and fluoroscopy.

NCT ID: NCT02265835 Completed - Clinical trials for Lung Transplantation

Anastomotic Airway Complications After Lung Transplantation

Start date: January 2014
Phase: N/A
Study type: Observational

Retrospective analysis of data concerning anastomotic airway complications after lung transplantation.

NCT ID: NCT01963377 Completed - Bronchoscopy Clinical Trials

Toward the Development of a Bronchoscope With a Dedicated O2 Channel ?

Start date: January 2013
Phase: N/A
Study type: Interventional

Feasibility of using an extra bronchoscopic channel for supplementation of oxygen will be studied by comparing O2-supplementation by nasal cannulae versus O2-supplementation through aspiration channel of the bronchoscope.

NCT ID: NCT01853904 Completed - Bronchoscopy Clinical Trials

Utility of Syringe Based Suction Versus Channel Suction in Bronchoalveolar Lavage

Start date: July 2012
Phase: N/A
Study type: Interventional

Bronchoalveolar lavage (BAL) is a common technique among pulmonologists. Its goal is to collect cells from alveolar units. This is done by wedging a flexible bronchoscope in a bronchus, instilling saline, and removing the saline via suction. Two techniques are currently used for suctioning: syringe based and channel suction. The investigators concern is that channel suction creates too much force and there is collapsing of the airways which results in decreased fluid removal as well as cell sampling. The investigators propose that syringe based suctioning will not only return more of the instilled fluid but also more cells from the alveoli.