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Bronchoscopy clinical trials

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NCT ID: NCT00915941 Completed - Bronchoscopy Clinical Trials

Exploratory Study of Potential Pulmonary Aspiration Markers From Bronchoalveolar Lavage Fluid

Pepsin
Start date: January 2009
Phase: N/A
Study type: Observational

The purpose of this study is to learn if chemicals from the mouth or stomach can be found in the lungs. This may suggest a process called aspiration. This study may help us understand if aspiration plays a role in different lung diseases.

NCT ID: NCT00861835 Completed - Bronchoscopy Clinical Trials

Trial of Rapid On-Site Evaluation of Transbronchial Needle Aspirate (TBNA)

Start date: November 2004
Phase: N/A
Study type: Interventional

Purpose: Previous studies suggested an increased diagnostic yield for bronchoscopic (FB) transbronchial needle aspirate (TBNA) specimens from mediastinal lymph nodes when using rapid on-site evaluation by cytopathology (ROSE) but were limited by lack of randomization. The investigators performed the first randomized-prospective trial comparing ROSE(R) to no on-site cytopathology assessment (NR). Methods: All patients referred were eligible. 78 patients were randomized to R or NR groups. For R procedures, further specimens were deferred until results were available from the on-site cytopathologist. Diagnoses made by all procedures were recorded. The primary end-points were specimen adequacy and diagnostic yield.

NCT ID: NCT00839371 Completed - Bronchoscopy Clinical Trials

Bronchoscopy and Bispectral Index (BIS) - Guided Sedation

Start date: January 2005
Phase: Phase 4
Study type: Interventional

Bronchoscopy is performed on a daily basis for diagnostic and therapeutic purposes. This procedure may cause anxiety and discomfort requiring the use of sedative drugs. In this study the investigators titrate the administration of sedatives using bispectral analysis of the EEG. The investigators compared 2 drugs, propofol versus midazolam regarding patient subjective tolerance, recovery of brain function, safety and operator's satisfaction.

NCT ID: NCT00684684 Completed - Bronchoscopy Clinical Trials

Safety and Feasibility Study of the Chartis System

Start date: May 2008
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the safety and feasibility of the Chartis System in measuring air flow and pressures in isolated lung compartments during bronchoscopy.

NCT ID: NCT00394537 Completed - Bronchoscopy Clinical Trials

Labetalol to Prevent Hypertension and Tachycardia During Fiberoptic Bronchoscopy

Start date: n/a
Phase: Phase 4
Study type: Interventional

Passing a bronchoscope through the airways frequently causes a stress response even though patients are sedated. This stress response is usually an increase in pulse and blood pressure, which may have undesirable effects on the heart and circulation. We plan to give patients labetalol (a beta blocker which reduces pulse and blood pressure) in addition to normal sedation, to patients undergoing bronchoscopy in our department.

NCT ID: NCT00306722 Completed - Anesthesia Clinical Trials

An Effectiveness and Safety Study of AQUAVAN® Injection (Fospropofol Disodium) for Sedation During Flexible Bronchoscopy

Start date: April 2006
Phase: Phase 3
Study type: Interventional

Very often patients receive medication before a diagnostic, therapeutic, or surgical procedure to help them relax, keep them calm, and to relieve them from pain. This is called procedural sedation. During procedural (mild-to-moderate) sedation, a patient is first given a pain-relief medication (analgesic) and then a medication to help him/her relax and keep him/her calm (sedative). Propofol is the drug commonly used for sedation because it releases immediately into the blood stream and causes fast sedation. AQUAVAN (fospropofol disodium) is made as a slow release version of propofol with a longer duration of effect.