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Icotinib for Completed Resected IB NSCLC With EGFR Mutation — CORIN  

Lung Neoplasms Clinical Trial

Official title:
A Randomized, Phase II Trial of Icotinib Versus Observation as Adjuvant Treatment in Stage IB Non-Small Cell Lung Cancer Harboring Activating Epidermal Growth Factor Receptor Mutation

Clinical Trial Summary

This phase II trial studies how well icotinib works in treating patients with completely resected stage IB NSCLC harboring EGFR mutation.

Clinical Trial Description

Adjuvant chemotherapy have shown little evidence of survival benefit in patients with stages IB non-small cell lung cancer (NSCLC) after complete resection. Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) show great efficacy in patients with EGFR mutant non-small cell lung cancer (NSCLC). Icotinib is a novel EGFR-TKI developed by a group of Chinese scientists and clinician. In the phase III ICOGEN trial, icotinib had non-inferiority efficacy to gefitinib with better safety. This study is studying icotinib to see how well it works in treating patients with fully resected stage IB NSCLC harboring EGFR mutation. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02264210
Study type Interventional
Source Sun Yat-sen University
Contact Si-Yu Wang, MD
Phone +86 20 87343314
Email wsysums@163.net
Status Recruiting
Phase Phase 2
Start date January 2015
Completion date December 2025
View Details
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