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NCT03820427 Clinical Trial

Evaluation of Novel Lung Function Parameters in Patients With Bronchial Asthma

Bronchial Asthma Clinical Trial

Official title:
Evaluation of Novel Lung Function Parameters in Patients With Bronchial Asthma

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT03820427
Other study ID # MBW-asthma
Secondary ID
Status Completed
Phase
First received
Last updated
Start date August 2015
Est. completion date December 2018

Study information
Verified date January 2019
Source Universitätsmedizin Mannheim
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

Current guideline-based criteria defining bronchial asthma do not always meet the challenges set by the complex pathophysiology of the disease. The investigators therefore aimed to evaluate novel or not widely used functional diagnostic approaches for the detection and therapeutic monitoring of patients with asthma.

Recruitment information / eligibility
Status Completed
Enrollment 147
Est. completion date December 2018
Est. primary completion date December 2018
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria:

- known or suspected bronchial asthma

- known or suspected obstructive ventilation disorder

- pulmonary healthy controls

Exclusion Criteria:

- pregnancy

- inability to participate

Study Design

Related Conditions & MeSH terms

Intervention

Diagnostic Test:
• impulse oscillometry
impulse oscillometry
• multiple breath washout test
multiple breath washout test
• body plethysmography
body plethysmography

Locations
Country Name City State
n/a

Sponsors (1)
Lead Sponsor Collaborator
Universitätsmedizin Mannheim

Outcome
Type Measure Description Time frame Safety issue
Primary Global ventilation heterogeneity lung clearance index (LCI) derived from sulphur hexafluoride multiple breath washout 30 minutes
Primary Local ventilation heterogeneity Sacin, Scond (Phase III slopes) derived from sulphur hexafluoride multiple breath washout 30 minutes
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