Clinical Trials Logo

Clinical Trial Summary

Background: After total knee replacement (TKR) surgery, patients often experience intense levels of pain, stress, and anxiety that can adversely affect postoperative recovery. Diaphragmatic breathing exercise (DBE) may help patients manage pain and emotional distress.

Aim: The aim of this study was to investigate the effect of DBE on pain, anxiety, and depression in patients undergoing TKR.

Methods: The study population consisted of patients who underwent TKR surgery in the orthopedic ward of Çankırı State Hospital between May and August 2019. The study sample included a total of 38 patients satisfying the inclusion criteria. Stratified randomization was used to assign the patients into sex-matched intervention group (n=19) and control group (n=19). Patients in the intervention group were also trained in the DBE procedure. Pain scores were evaluated at 1, 2, 4, 8, 12, and 24 hours postoperatively, while the anxiety and depression was applied on the postoperative day 2. Data were analyzed using descriptive statistics, Chi-square test, and Mann-Whitney U test.


Clinical Trial Description

TKR is one of the most common orthopedic surgical procedures. Because TKR involves extensive muscle and bone repair, it is known to be one of the most painful operations. Moreover, as prosthetic surgery is an elective procedure, patients delay and experience anxiety about surgery due to their experiences with severe pain. This leads to chronic fear of pain and negative thought patterns. Inadequate use of analgesics and poor pain management after surgery can cause delayed mobilization, increased risk of venous thrombosis, insufficient wound healing, prolonged hospital stay, unnecessary psychological distress, and lower patient satisfaction. Many patients experience psychological problems such as depression, anxiety, discouragement, negative feelings, crying, frustration, lack of motivation, fatigue, moodiness, irritability, despair, and helplessness. Patients have expressed a need for social or psychological support. In order for patients to avoid such pain-related complications, they must be taught how to cope with pain.

The severe pain, anxiety, and stress patients experience following TKR surgery may impact their postoperative recovery. Studies have shown that nonpharmacological interventions for postoperative pain reduce pain intensity and opioid use. One of these nonpharmacological methods is diaphragmatic breathing exercises (DBE). Also known as diaphragmatic breathing or deep breathing, DBE is an effective holistic mind-body training to cope with stress and psychosomatic conditions. DBE involves contraction of the diaphragm and expansion of the belly to deepen inhalation and exhalation, which consequently decreases breathing rate and maximizes blood gas concentrations.

DBE plays an important role in pain signaling, autonomic activation, emotional regulation, acid-base equilibrium, and anti-inflammatory processes. DBE has been shown to enhance emotions, effectively reduce anxiety and its symptoms, and alleviate negative emotions such as depression, stress, and anger. There are few studies in the literature on the effect of DBE on patients who underwent TKR. One of these is a semi-experimental study that evaluated the effect of relaxation intervention (breathing exercises and guided imagery) on patients who underwent TKR. They authors reported that relaxation techniques were effective in managing patients' pain and anxiety. Another study evaluating the effect of relaxation techniques and back massage in patients who underwent TKR and total hip replacement (THR) showed that these techniques reduced patients' pain and anxiety during bedrest. Investigated the effect of a DBE program in patients with OA and found that DBE had no effect in alleviating pain or improving physical function.

A few studies have used DBE to prevent pain and sensory tension in patients who underwent TKR. However, different relaxation techniques were used in addition to DBE in these studies. To the best of our knowledge, no studies have examined the efficacy of DBE alone. Given the rising incidence of TKR, it is imperative that we strengthen our arsenal of effective interventions against the pain and psychological problems associated with this procedure. The aim of the present study was to evaluate the effect of DBE on pain, anxiety, and depression in patients who underwent TKR. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04225169
Study type Interventional
Source Çankiri Karatekin University
Contact
Status Completed
Phase N/A
Start date May 23, 2019
Completion date August 28, 2019

See also
  Status Clinical Trial Phase
Completed NCT02243527 - Respiratory Muscles and Inspiratory Muscle Training N/A
Completed NCT00997737 - Diaphragm Activity During Incentive Spirometry and Diaphragmatic Breathing Phase 1
Not yet recruiting NCT04366414 - Breathing Protocol in Breath-hold Divers N/A
Completed NCT06239181 - Effect of Breathing Exercises Before Coronary Angiography N/A
Completed NCT06134778 - Effect of Inspiratory Muscle Training on Cardiopulmonary Capacity in Wheelchair Rugby Athletes N/A
Completed NCT06021106 - Respiratory Exercise to Copd With Virtual Reality Glasses on Dyspnea, Anxiety and Qualıty of Life N/A
Completed NCT03499054 - Breathing Exercises to Improve Fatigue and Quality of Life in Hemodialysis Patients N/A
Completed NCT05428722 - Deep Breathing Exercise With Incentive Spirometer Started in the Preoperative Period N/A
Completed NCT05936788 - Comparative Effects of ACBT and Diaphragmatic Breathing on Pulmonary Function and Sputum Diary After CABG N/A
Not yet recruiting NCT05875545 - Effects of Breathing Exercises in Women With Chronic Pelvic Pain N/A
Completed NCT06121596 - Relaxation Effects of Personalized Breathing Exercises for Healthy College Students N/A
Completed NCT02720380 - Buteyko Method for Children With Asthma N/A
Completed NCT02828735 - Respiration Patterns With Impedance in LINQ N/A
Completed NCT02604147 - Inspiratory Muscle Training in Wheelchair Basketball Players N/A
Completed NCT03936348 - Effects of an Exercise Rehabilitation Programme With a Nasal Inspiratory Restriction Device in COPD Patients N/A
Recruiting NCT04270162 - New Intervention Protocol With Inspirometer Versus 2 Modalities of Pulmonary Intervention: INSPUL-REHAB N/A
Recruiting NCT05178056 - Spinal Cord Stimulation and Respiration After Injury N/A
Recruiting NCT04558151 - Randomized-controlled Trial of Preoperative Inspiratory Muscle Training on Postoperative Complications N/A
Completed NCT05572827 - The Efficiency of Breathing Exercises N/A
Completed NCT03516344 - Effect of Osteopathic Manipulations on Portal Venous Flow N/A