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Breastcancer clinical trials

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NCT ID: NCT04993040 Completed - Breastcancer Clinical Trials

A PK Study of Oraxol in Breast Cancer Patients

Start date: April 22, 2019
Phase: Phase 1
Study type: Interventional

This is a multicenter, open-label, single-arm PK study in approximately 24 breast cancer patients for whom paclitaxel treatment is indicated.

NCT ID: NCT03165955 Completed - Breastcancer Clinical Trials

A Clinical Study to Determine the Pharmacokinetics of Oraxol in Breast Cancer Patients

Start date: May 9, 2017
Phase: Phase 1
Study type: Interventional

This is a multicenter, open-label, single-arm PK study in patients for whom paclitaxel treatment is indicated.

NCT ID: NCT03066947 Completed - Breast Neoplasm Clinical Trials

SV-BR-1-GM in Metastatic or Locally Recurrent Breast Cancer

Start date: May 5, 2017
Phase: Phase 1/Phase 2
Study type: Interventional

This is a single arm, open label study of SV-BR-1-GM, a targeted immunotherapy for breast cancer. Eligible patients will have histological confirmation of breast cancer with recurrent and/or metastatic lesions. The treatment regimen includes a pre-treatment with low-dose cyclophosphamide 2-3 days before the inoculation; inoculation in 4 sites on the thighs and upper back; and post-treatment inoculation of Interferon-alpha-2b into the sites of inoculation ~2 and ~4 days after the inoculation. These is repeated every 2 weeks for one month (3 treatments), then monthly for up to one year. Standard tumor assessments are performed at baseline and then every 2-3 months.

NCT ID: NCT03030677 Completed - Breastcancer Clinical Trials

Establishing Technique for PECS2 Catheter Insertion

ETCI
Start date: November 1, 2018
Phase: N/A
Study type: Interventional

The investigators are trying to establish an easy technique for insertion of a catheter for continuous infusion while performing pectoral type 2 (serratus) block, as a post operative pain controlling measure for cases undergoing simple mastectomy, using ultrasound guidence

NCT ID: NCT03023007 Completed - Mastectomy Clinical Trials

Study Evaluating the Efficacy of Loco-regional Anaesthesia PECS on Chronic Pain of a Mastectomy

PECS
Start date: April 3, 2017
Phase: N/A
Study type: Interventional

A non-randomized, mono-centric, prospective interventional study that will assess the efficacy of the loco-regional anesthesia PECS on the rate of chronic pain, 6 month after a patient will have either received a mastectomy or a mastectomy associated with axillary nodes dissection, and/or a reconstruction by prosthesis.

NCT ID: NCT03014076 Completed - Breastcancer Clinical Trials

Immunotherapy Vaccine and Herceptin in Breast Cancer

Start date: January 2008
Phase: Phase 1
Study type: Interventional

The purpose of this trial is to determine if combination immunotherapy with HER2/neu GP2 peptide + GM-CSF vaccine and trastuzumab is safe and immunologically effective in treatment of patients with HER2/neu over-expressing breast cancer in the adjuvant setting. While not a primary endpoint, time to recurrence is measured for enrolled subjects. The objectives of the study are the following: - Assess safety and document local and systemic toxicity to combination immunotherapy with GP2 peptide + GM-CSF vaccine and trastuzumab - Evaluate the in vitro and in vivo immunologic responses to combination immunotherapy of GP2 peptide + GM-CSF vaccine and trastuzumab - Determine maximum tolerated dose and optimal biologic dose for the combination immunotherapy of GP2 peptide + GM-CSF vaccine and trastuzumab

NCT ID: NCT03012893 Completed - Breastcancer Clinical Trials

Identification of C7; Evaluations of 2 Sonographic Methods Using a Transverse and a Sagittal Scan.

Start date: December 2016
Phase: N/A
Study type: Interventional

To determine the accuracy of two techniques (transverse scan and sagittal scan) using ultrasonography to identify C7 spinous process compare to the fluoroscope (standard technique)

NCT ID: NCT03012152 Completed - Breastcancer Clinical Trials

A Comparative Study Between Oncoplastic Breast Surgery and Standard Conservative Surgery:Margin Status and Patient Satisfaction

Start date: September 2012
Phase: N/A
Study type: Interventional

This non randomized study is a comparative study between standard conservative breast surgery and oncoplastic surgery as regard margin status and patient satisfaction.

NCT ID: NCT03010371 Completed - Emotional Disorder Clinical Trials

Presential Vs Online Group-based Psychosocial Treatment for Breast Cancer Survivors.

PSONLINE
Start date: January 2016
Phase: N/A
Study type: Interventional

This multicenter study is a sequential RCT which aims to prove, in the first stage, the efficacy of a face-to-face Positive Psychotherapy in Cancer (PPC) group compared to a Cognitive Behavioral Stress Management (CBSM) group. In the second stage, the common face-to-face version of the PPC will be compared with its online version via videoconference (Online group Positive Psychotherapy, OPPC) among a group of primary breast cancer survivors. The principal dependent variables assessed will be emotional distress, post-traumatic growth (PTG) and quality of life (QoL). Some treatment predictors of psychosocial response will be explored. Lastly, an economic analysis focused on the Quality Adjusted Life Years (QALY) will be carried out at each stage. For the first stage, we hypothesize that the PCC group would achieve similar efficacy in reducing participants' distress compared to the CBSM group, while the PCC group would show greater improvement in PTG than the CBSM group. For the second stage, it is hypothesized that the OPCC would achieve similar efficacy in all psychosocial variables and guarantee equivalent retention and adherence compared to face-to-face PPC.

NCT ID: NCT02996240 Completed - Breastcancer Clinical Trials

Breast, Omega 3 Free Fatty Acid, Ph 0

Start date: June 12, 2017
Phase: N/A
Study type: Interventional

Assess the impact of dietary omega 3 free fatty acids breast cancer patients.