Clinical Trials Logo
  1. Home
  2. Brain Tumor, Primary
  3. NCT05092802

The Efficacy of HLX208 (BRAF V600E Inhibitor) for Refractory Primary Brain Tumors With BRAF Mutation After First-line Treatment

Brain Tumor, Primary Clinical Trial

Official title:
An Open-label, Multicenter Phase II Clinical Study to Evaluate Safety, Efficacy and PK of HLX208 for Refractory Primary Brain Tumors With BRAF Mutation

Clinical Trial Summary

An open-label, multicenter phase II clinical study to evaluate safety, efficacy and PK of HLX208 for refractory primary brain tumors with BRAF mutation

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05092802
Study type Interventional
Source Shanghai Henlius Biotech
Contact Jinming Yu
Phone 0531-67626819
Email sdyujinming@126.com
Status Recruiting
Phase Phase 2
Start date December 23, 2021
Completion date May 30, 2024
View Details
See also
  Status Clinical Trial Phase
Recruiting NCT06057168 - Performance of Elucirem® in DSC-MRI Perfusion of Brain Gliomas Phase 3
Recruiting NCT04427384 - Registry of Patients With Brain Tumors Treated With STaRT (GammaTiles)
Completed NCT03323450 - Cognitive Remediation Therapy for Brain Tumor Patients: Improving Working Memory N/A
Completed NCT00241670 - Fluorescence-guided Resection of Malignant Gliomas With 5-Aminolevulinic Acid Phase 3
Completed NCT02599142 - Comparing Immobilisation Shells in Cranial Radiotherapy N/A
Not yet recruiting NCT01445691 - More Complete Removal of Malignant Brain Tumors by Fluorescence-Guided Surgery Phase 2
Recruiting NCT06282562 - FeelFit: High-intensity Interval Training to Improve Self-reported Physical Fitness in Brain Tumor Patients N/A
Recruiting NCT06322342 - Phase 2 Ascending Dose Safety and Efficacy Study of RVP-001, a Manganese-based MRI Contrast Agent Phase 2
Completed NCT00001574 - A Pilot Study of 1H-Nuclear Magnetic Resonance Spectroscopic Imaging in Pediatric Patients With Primary and Metastatic Brain Tumors
Completed NCT04365647 - Intra-operative Variation in Size of Brain Tumors After Craniotomy
Not yet recruiting NCT06185686 - Radiation Induced Alterations in Resting State Brain Networks in Pediatric Brain Tumor Patients
Withdrawn NCT04776980 - Multimodality MRI and Liquid Biopsy in GBM Early Phase 1
Completed NCT03262636 - Two-Part Study to Evaluate the Safety and Efficacy of Image Guided Surgery Using Indocyanine Green for Intramolecular Imaging of Nervous System Tumors Compared to Standard of Care, (TumorGlow) Phase 1
Active, not recruiting NCT02006407 - A Pilot Study to Evaluate Neurocognitive Injury and Longitudinal Changes in White Matter During Radiation Therapy in Children With Primary Brain Tumors N/A
Recruiting NCT03213002 - Oral Capecitabine and Temozolomide (CAPTEM) for Newly Diagnosed GBM Phase 1/Phase 2
Recruiting NCT05775458 - Glutamate Excitotoxicity and Its Role in Glioblastoma Biology
Terminated NCT04901806 - Study of PBI-200 in Subjects With NTRK-Fusion-Positive Solid Tumors Phase 1
Recruiting NCT03373487 - Cognitive Rehabilitation in Brain Tumor Patients After Neurosurgery N/A
Not yet recruiting NCT06106997 - Clinical Feasibility of Brain Radiotherapy Using Synthetic CTs in an MRI-only Workflow N/A
Recruiting NCT05254197 - SeOuL cOhort of Brain Tumor MONitoring Study (SOLOMON)