Brain Injuries Clinical Trial
Official title:
Reducing Scan Times and Improving Care Through Quantitative Imaging: Evaluating the Efficacy of SyMRI in Clinical Pediatric Populations
Synthetic MR Technologies has created a quantified imaging solution - SyMRI - to enable radiologists to acquire quantified images and always obtain the best contrast images. This study represents an attempt to assess the clinical utility of this software.
Typical magnetic resonance imaging (MRI) involves taking many images called 'contrasts' to
look at the body in different ways. Standard scan settings are usually good enough for a
radiologist to review. The best settings often change with the age of the patient and their
health, and are time consuming to determine. Quantified imaging is an alternative to
contrast-based imaging which explicitly measures tissue properties and can be used to create
almost any contrast. This method of imaging has been held back by a lack of the right
software. Synthetic MR Technologies has created a quantified imaging solution - SyMRI - to
enable radiologists to acquire quantified images and always obtain the best contrast images.
The objective of this study is to evaluate SyMRI in a pediatric population to determine if
Sickkids would be interested in purchasing this product / support Health Canada approval.
Specifically, the investigators are interested in determining if SyMRI is clinically useful:
- Is synthetic imaging quality comparable / better than conventional imaging?
- Qualitative - Are radiologists more confident using synthetic MR vs conventional
- Quantitative - Signal-to-noise (SNR) and Contrast-to-noise (CNR)
- To what extent can total exam times be reduced?
- Is the software user friendly and would investigators use it?
;
Status | Clinical Trial | Phase | |
---|---|---|---|
Enrolling by invitation |
NCT05542108 -
Adding Motion to Contact: A New Model for Low-cost Family Centered Very-early Onset Intervention in Very Preterm-born Infants
|
N/A | |
Completed |
NCT03400904 -
Extubation Strategies in Neuro-Intensive Care Unit Patients and Associations With Outcome.
|
||
Completed |
NCT06073145 -
Transcranial Doppler Using Wearable Ultrasound Patch
|
||
Recruiting |
NCT03899532 -
Remote Ischemic Conditioning in Traumatic Brain Injury
|
N/A | |
Recruiting |
NCT06010823 -
Safety and Efficacy Evaluation of the Robotic Enhanced Error Training of Upper Limb Function in Post-stroke and Post TBI Participants
|
N/A | |
Not yet recruiting |
NCT05833568 -
Five-day 20-minute 10-Hz tACS in Patients With a Disorder of Consciousness
|
N/A | |
Withdrawn |
NCT04288076 -
The Brain and Lung Interaction (BALI) Study
|
N/A | |
Not yet recruiting |
NCT02756585 -
Computed Tomography Perfusion in Patients With Severe Head Injury
|
N/A | |
Completed |
NCT03162484 -
Physical Activity and Chronic Acquired Brain Injury
|
N/A | |
Terminated |
NCT01430988 -
Observational Study of the BrainScope® Ahead™ M-100 in UK Emergency Department Patients With Head Injury
|
N/A | |
Completed |
NCT01093053 -
Mind-Body Skills Groups for the Treatment of War Zone Stress in Military and Veteran Populations
|
N/A | |
Completed |
NCT00975338 -
The LETS Study: A Longitudinal Evaluation of Transition Services
|
||
Completed |
NCT00878631 -
Feasibility Trial of Traumatic Brain Injured Patients Randomized in the Prehospital Setting to Either Hypertonic Saline and Dextran Versus Normal Saline
|
Phase 2/Phase 3 | |
Completed |
NCT03166722 -
Cerebral Regional Tissue Oxygen Saturation to Guide Oxygen Delivery in Preterm Neonates During Immediate Transition
|
N/A | |
Not yet recruiting |
NCT04478812 -
Tbit System Precision and Correlation of Different Blood Samples
|
N/A | |
Recruiting |
NCT05443542 -
VIrtual Reality in Cognitive Rehabilitation of Processing Speed for Persons With ABI
|
N/A | |
Recruiting |
NCT05309005 -
Virtual Reality and Social Cognition After Acquired Brain Injury
|
||
Completed |
NCT02702635 -
Measuring Blood Flow Characteristics Using Dynamic Contrast Enhanced Magnetic Resonance Imaging
|
N/A | |
Withdrawn |
NCT04247321 -
Non-invasive Near-infrared Spectroscopy (NIRS) Versus Invasive Licox Intracranial Pressure
|
N/A | |
Not yet recruiting |
NCT04386525 -
Omega 3 and Ischemic Stroke; Fish Oil as an Option
|
Phase 4 |