NTS-WBRT in Brain Metastases

Status Recruiting

Clinical Trial Summary

This research is being done to assess the quality of life and symptom burden in participants who receive (normal tissue sparing whole brain radiation therapy (NTS-WBRT). This research study involves: - NTS-WBRT (normal tissue sparing whole brain radiation therapy) - Memantine standard of care drug

Clinical Trial Description

This is a Phase 2 trial testing the safety and effectiveness of NTS-WBRT (normal tissue sparing whole brain radiation therapy) in treating brain metastases. NTS-WBRT is a targeted radiation therapy that further reduces radiation dose to tissue that does not need radiation therapy treatment. The research study procedures include screening for eligibility and study treatment including evaluations and follow up visits. It is expected that about 41 people will take part in this research study. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05013892
Study type	Interventional
Source	Massachusetts General Hospital
Contact	Helen A Shih, MD, MS, MPH
Phone	(617) 724-9627
Email	hshih@mgh.harvard.edu
Status	Recruiting
Phase	Phase 2
Start date	February 8, 2022
Completion date	December 31, 2027

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