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Stereotactic Radiotherapy Plus Temozolomide for Refractory Brain Metastases — SRTRBM  

Brain Metastases Clinical Trial

Official title:
Fractionated Stereotactic Radiotherapy Combined With Temozolomide for Refractory Brain Metastases: A Single-arm, Single-center Phase II Trial

Clinical Trial Summary

This clinical trial was designed to investigate the efficiency and toxicity of fractionated stereotactic radiotherapy(FSRT) combined with Temozolomide(TMZ) for refractory brain metastases.

Clinical Trial Description

This is a single-arm, single center, phase II trial to investigate the feasibility and toxicity of FSRT plus TMZ for refractory brain metastases, which are defined as A: multiple brain metastases(≥3 lesions); B: large brain metastases(with one lesion's volume is no smaller than 6cc or the longest diameter is no shorter than 3cm); C: meningeal metastases. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02654106
Study type Interventional
Source Chinese Academy of Medical Sciences
Contact
Status Completed
Phase Phase 2
Start date October 2011
Completion date November 2015
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