Brain Injury Clinical Trial
Official title:
Phase 2 Study of Neuropsychological Therapy for Patients With Acquired Brain Injury Focusing on the Role of Psychosocial Adjustment Using a Cognitive Behavioral Approach
Acquired brain injury can result in impaired everyday functioning as well as psychosocial problems, including depressive symptoms, irritability, or negative self-concept. The purpose of this study is to determine whether a combination of neuropsychological and cognitive behavioral therapy is effective in the treatment of these sequelae.
Acquired brain injury (ABI) commonly results in persistent cognitive, emotional and
motivational problems. About 50% of patients involved develop psychiatric illness, most
likely in the first year following ABI, which is associated with reduced psychosocial
functioning and less favorable rehabilitation outcome. Treatment of these complex conditions
requires a combination of neuropsychological and psychotherapeutic intervention techniques.
This study aims at evaluating a combination of neuropsychological intervention methods,
which include developing and using compensation strategies for cognitive impairments
(attention, memory and executive functions), and psychotherapeutic intervention focusing on
emotion regulation, developing positive self-concepts and adjustment of life-goals. These
therapeutic interventions are modularized and patients are assigned to intervention modules
according to results of objective neuropsychological testing and interviews.
;
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
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