Clinical Trials Logo

Clinical Trial Summary

Acquired brain injury can result in impaired everyday functioning as well as psychosocial problems, including depressive symptoms, irritability, or negative self-concept. The purpose of this study is to determine whether a combination of neuropsychological and cognitive behavioral therapy is effective in the treatment of these sequelae.


Clinical Trial Description

Acquired brain injury (ABI) commonly results in persistent cognitive, emotional and motivational problems. About 50% of patients involved develop psychiatric illness, most likely in the first year following ABI, which is associated with reduced psychosocial functioning and less favorable rehabilitation outcome. Treatment of these complex conditions requires a combination of neuropsychological and psychotherapeutic intervention techniques.

This study aims at evaluating a combination of neuropsychological intervention methods, which include developing and using compensation strategies for cognitive impairments (attention, memory and executive functions), and psychotherapeutic intervention focusing on emotion regulation, developing positive self-concepts and adjustment of life-goals. These therapeutic interventions are modularized and patients are assigned to intervention modules according to results of objective neuropsychological testing and interviews. ;


Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment


Related Conditions & MeSH terms


NCT number NCT00596765
Study type Interventional
Source Philipps University Marburg Medical Center
Contact
Status Completed
Phase N/A
Start date September 2007
Completion date March 2015

See also
  Status Clinical Trial Phase
Completed NCT02710123 - Sub-Threshold Exercise Treatment for Adolescents With Sports Related Concussion N/A
Recruiting NCT02777060 - Exploring the Effectiveness of Sensor-based Balance Training on Patient Outcome Measures N/A
Completed NCT02262286 - MIND (Management of Traumatic Brain Injury Diagnosis) N/A
Completed NCT01461902 - Vasospasm in Pediatric Traumatic Brain Injury N/A
Recruiting NCT01198964 - Optimization of Human Cortical Stimulation
Active, not recruiting NCT01207050 - Effect of Rozerem on Sleep Among People With Traumatic Brain Injury Phase 4
Completed NCT01201863 - Neuroendocrine Dysfunction in Traumatic Brain Injury: Effects of Testosterone Therapy Phase 4
Completed NCT00875329 - Traumatic Brain Injury (TBI) Screening Instruments N/A
Completed NCT01059890 - Cerebral Antibiotics Distribution After Acute Brain Injury Phase 1
Completed NCT01035606 - Training in Goal-directed Attention Regulation for Individuals With Brain Injury N/A
Completed NCT00571623 - Automated Chest Physiotherapy to Improve Outcomes in Neuro N/A
Completed NCT00336466 - The Erythropoietin NeuroProtective Effect: Assessment in CABG Surgery (TENPEAKS) Phase 2
Recruiting NCT05105763 - Biofeedback Gait Retraining for Stiff Knee Gait Correction N/A
Recruiting NCT02495558 - Cough Assessment in Patients With Severe Acquired Brain Injury N/A
Completed NCT02100592 - Early Verticalization in neuroICU With ERIGO: a Safety and Feasibility Study Phase 1/Phase 2
Completed NCT00797680 - Duration of Hypothermia for Neuroprotection After Pediatric Cardiac Arrest Phase 2
Completed NCT00018499 - Genotype Influence on Recovery After Traumatic Brain Injury N/A
Recruiting NCT02567201 - Electrophysiological Evaluation of Voluntary Attention N/A
Withdrawn NCT05581927 - Whole-Body Hypothermia for Neonates With Hypoxic-Ischemic Encephalopathy(HIE) N/A
Completed NCT02615119 - Neural Basis of Meal Related Interoceptive Dysfunction in Anorexia Nervosa N/A