Restoration vs. Compensation in Neurovisual Rehabilitation of Visual Field Defects

Brain Injuries, Traumatic Clinical Trial

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04043429
• Other study ID #: VRT100
• Status: Completed
• Phase: Phase 2
• Start date: January 2003
• Est. completion date: January 2005

Study information

• Verified date: July 2019
• Source: University of Magdeburg
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Visual field defects (VFD) are a frequent effect of cerebral lesions especially after posterior cerebral artery stroke. The present study was conducted to compare effects of vision restoration training (VRT) and compensation training (Visual Exploration Training, VET) on visual field performance.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 86
• Est. completion date: January 2005
• Est. primary completion date: January 2005
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 80 Years

Eligibility

Inclusion Criteria:

• Visual field defects after brain damage

• lesion age above 6 months

• documented brain lesions due to ischemic stroke, hemorrhage or tumor demonstrated by computer tomography or by magnet resonance imaging

Exclusion Criteria:

• hemispatial neglect

• complete blindness

• severe psychotic diseases

• serious drug abuse

• chronic degenerative diseases (dementia, multiple sclerosis)

• severe motor impairments

• noticeable low intelligence influencing proper comprehension of diagnostic and training instructions

• considerable impaired vision (visual acuity below 0.1 generated by amblyopia, opacity of cornea or lens, maculopathy and other retinal diseases where vision impairment is expected in the next month (e.g. subretinal neovascularisation, retinitis pigmentosa, diabetic retinopathy)

• inability to fixate due to central scotoma, pathological nystagmus or other forms of fixation disabilities

Related Conditions & MeSH terms

• Brain Injuries
• Brain Injuries, Traumatic
• Hemianopia
• Hemianopsia

Intervention

Behavioral:
• Vision Restoration Training (VRT)

• Vision Exploration Training (VET)

Locations

Country	Name	City	State
Germany	Inst. f. Medical Psychology, Univ. of Magdeburg	Magdeburg

Sponsors (1)

Lead Sponsor	Collaborator
University of Magdeburg

Country where clinical trial is conducted

Germany, 

References & Publications (1)

Sabel BA, Gudlin J. Vision restoration training for glaucoma: a randomized clinical trial. JAMA Ophthalmol. 2014 Apr 1;132(4):381-9. doi: 10.1001/jamaophthalmol.2013.7963. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	High Resolution Perimetry - Detectection performance change before vs. after training (%)		3 months
Primary	Humphrey Field Analyzer (Static Perimetry) - Detectection performance change before vs. after training (%)		3 months