Brain and Central Nervous System Tumors Clinical Trial
Official title:
Phase II Study Trial Of Tarceva In Patients With Recurrent/Progressive Glioblastoma Multiforme
RATIONALE: Erlotinib may stop the growth of cancer cells by blocking the enzymes necessary
for cancer cell growth.
PURPOSE: Phase II trial to study the effectiveness of erlotinib in treating patients who
have recurrent or progressive glioblastoma multiforme.
OBJECTIVES:
- Determine the response rate of patients with recurrent or progressive glioblastoma
multiforme treated with erlotinib.
- Determine the progression-free and overall survival of patients treated with this drug.
OUTLINE: Patients receive oral erlotinib daily. Treatment continues in the absence of
disease progression or unacceptable toxicity.
Patients are followed for survival.
PROJECTED ACCRUAL: A total of 73 patients will be accrued for this study.
;
Masking: Open Label, Primary Purpose: Treatment
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