Clinical Trials Logo

Brachial Plexus Injury clinical trials

View clinical trials related to Brachial Plexus Injury.

Filter by:

NCT ID: NCT06437990 Enrolling by invitation - Clinical trials for Brachial Plexus Injury

Arteriovenous Loop Graft for Free Functional Gracilis Transfer in Brachial Plexus Surgery

Start date: November 19, 2015
Phase: N/A
Study type: Interventional

Free functional muscle transfer (FFMT) using the gracilis muscle as a donor muscle has become a standard treatment for reconstructing late-onset brachial plexus injuries. Successful implementation of this procedure relies on the availability of functional donor vessels in the injured limb to supply the muscle flap. However, some brachial plexus injuries are accompanied by subclavian or axillary artery injuries, which compromise the viability of the muscle flap due to insufficient vascular supply. To address this, arteriovenous (AV) loop grafts have been employed to extend donor vessels to the flap and have been utilized in various body regions, including the upper extremity. Despite their widespread use, AV loop grafts have not been previously utilized in FFMT for late-onset brachial plexus injuries with concurrent subclavian or axillary artery injuries. This study aimed to assess the feasibility of this surgical approach and report the long-term outcomes of the procedure.

NCT ID: NCT06313658 Recruiting - Clinical trials for Brachial Plexus Injury

Enhancing Functional Hand Recovery Through Nerve Reconstruction in Total Brachial Plexus Birth Injury

Start date: March 15, 2024
Phase:
Study type: Observational

Interpreting the published outcomes of hand function in total BPBI is confounded by a lack of clear documentation regarding detailed surgical findings and management strategies. Investigators have followed a well-defined protocol for surgical reconstruction with the primary objective being reinnervation of the lower trunk using the best available root. In this paper, Investigators outline the details of the strategy and provide a comprehensive analysis of the nerve reconstruction techniques and the resulting functional outcomes.

NCT ID: NCT06237270 Completed - Clinical trials for Brachial Plexus Injury

External Validation Study for Risk Prediction Model for Unsuccessful Elbow Flexion Recovery After Nerve Transfer Surgery in Patients With Brachial Plexus Injury

Start date: March 17, 2023
Phase:
Study type: Observational

The goal of this observational study is to validate a risk prediction model developed for unsuccessful elbow flexion recovery after nerve transfer surgery in patients with brachial plexus injury. The main question it aims to answer is how well a risk prediction model perform in a different dataset, which are patients with brachial plexus injury who underwent surgery in a different time period or a different hospital.

NCT ID: NCT05859178 Not yet recruiting - Clinical trials for Brachial Plexus Injury

Exercise Training for Brachial Plexus Injury Following Nerve Transfer

Start date: September 1, 2024
Phase: Phase 2
Study type: Interventional

Although peripheral nerve is capable of regrowth following injury, at only 1 mm/day, the slow rate represents a major barrier. Apart from rapid deterioration of the environment supportive of growth, denervated muscles become atrophic and bones osteoporotic. To successfully restore function, in addition to speeding up the nerve regeneration rate, treatments that can also restore muscle and bone mass are essential. Recently, in animal studies, the investigators showed that in addition to accelerating the speed of nerve regeneration, exercise training can also be used to restore muscle bulk and bone density. While promising, given the inter-species differences, the clinical utilities of this treatment need to be directly tested in humans. This will be done using a randomized controlled study design on patients with brachial plexus injury.

NCT ID: NCT05810077 Not yet recruiting - Clinical trials for Brachial Plexus Injury

Feasibility of Brachial Plexus Ultrasound in Evaluation of Patients With Brachial Plexus Injuries

Start date: June 2023
Phase:
Study type: Observational

Evaluation of ultrasound as a diagnostic tool in assessment of patients with brachial plexus injuries before undergoing surgical exploration

NCT ID: NCT05693038 Recruiting - Clinical trials for Brachial Plexus Injury

Brachial Plexus Injury After Prone Positioning

BPX
Start date: April 6, 2022
Phase:
Study type: Observational

The goal of this prospective observational study is to estimate the prevalence of brachial plexus injury after prone positioning in patients with ARDS and to evaluate the safety of swimmer position. The main questions it aims to answer are: - Could arm positioning during pronation play a role in the development of any nerve injury at the brachial plexus level? - Is swimmer position safe when adopted during prone positioning? Participants will be studied at selective time points using EMG assessment.

NCT ID: NCT05575674 Completed - Stroke Clinical Trials

Retrospective Study on Myoelectric Elbow-Wrist-Hand Orthosis User Outcomes

Start date: October 5, 2022
Phase:
Study type: Observational

The objective of this study is to retrospectively evaluate the outcomes and clinical benefits provided by this brace to adult patients with upper limb impairment or paralysis due to brachial plexus, stroke (CVA), spinal cord injury, or other neurological disease or injury.

NCT ID: NCT04959058 Not yet recruiting - Clinical trials for Brachial Plexus Injury

EVALUATION OF BRACHIAL PLEXUS IN DIFFERENT ARM POSITION

ELAST
Start date: July 15, 2021
Phase: N/A
Study type: Interventional

In daily life,people protect their tissues against ischemia by constantly changing positions. In situations that cause unconsciousness such as anesthesia,people cannot react to the stress or pressure due to immobility.This prolongation of immobility can lead to reversible or irreversible damage to the tissues.Therefore,not careful positioning in patients undergoing surgery can lead to serious complications.Peripheral nerve disorders are common in clinical practice.Electrodiagnostic studies continue to be the gold standard for the evaluation of nerve disorders.Elastography is a technique that measures the elastic properties of tissues as a new ultrasonography technology.Given the histological changes in diseased peripheral nerves, nerve elastography has begun to be studied as a noninvasive way to evaluate changes in nerve tissue composition.Elastography of the peripheral nerves has rarely been studied. Primary aim in this study is to compare the elastography values of the brachial plexus in different arm and head positions and to contribute to elucidating the mechanism of nerve damage due to position.American Society of Anesthesiologists (ASA) I-II volunteers between the ages of 18-65 will be recruited to the study.The bilateral brachial plexus of each volunteer will be examined.Participants with upper extremity or cervical trauma, muscle weakness,cervical disc herniation or a history of spine or cranial surgery, neuromuscular disease, clinical diagnosis of brachial plexopathies, hyperlipidemia,diabetes mellitus or radiotherapy history in the cervical region,body mass index> 35 will not be taken.Before the procedure, the muscle strength of the upper extremity and cervical muscles will be examined and volunteers with muscle weakness will be excluded from the study.Measurements will be made together by two researchers who have at least 5 years of experience in ultrasonography.Measurements will be made in 3 different positions.When the arm and head are in neutral position, the head is turned to the opposite side and the head is turned to the opposite side, the brachial plexus in the supraclavicular region will be visualized by ultrasonography while the arm is in hyperabduction.The area between the upper boundary and the lower boundary of the plexus will be marked, and the values will be taken 5 times consecutively with the share wave elastography method and the elastic modulus,shear wave velocity will be recorded.

NCT ID: NCT04939233 Recruiting - Clinical trials for Brachial Plexus Injury

Robotic Hand Orthosis Providing Grasp Assistance for Patients With Brachial Plexus Injuries

Start date: July 1, 2021
Phase: N/A
Study type: Interventional

The proposed research, the development of an innovative robotic hand orthosis with intelligent grasping control, is relevant to public health as it will restore a large measure of functionality to the paralyzed hand of a person who has suffered a brachial plexus injury. The proposed orthosis will utilize novel technology that will result in a device that is compact, portable, dexterous, and intuitively controllable while overcoming the disadvantages of previously developed orthoses that rendered them difficult to use. The restoration of functionality to ones hands will significantly improve their quality of life as well as their ability to again participate in the workforce and complete dexterous activities in their daily lives.

NCT ID: NCT04933149 Enrolling by invitation - Clinical trials for Brachial Plexus Injury

Ketamine Infusion for Neuropathic Pain in Brachial Plexus Injuries

Start date: December 15, 2021
Phase: Phase 4
Study type: Interventional

The purpose of this study is to assess pre- and postoperative neuropathic pain in patients with traumatic brachial plexus injuries to determine if intraoperative ketamine infusion affect neuropathic pain associated with avulsion injuries of the brachial plexus.