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Bowel Cancer clinical trials

View clinical trials related to Bowel Cancer.

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NCT ID: NCT03479645 Completed - Colon Cancer Clinical Trials

Serial SMS Reminders and an Opt-out Mailed FIT Kits to Improve Colorectal Screening Participation: A Single Center RCT

Start date: March 23, 2018
Phase: N/A
Study type: Interventional

This pilot study is a 2-armed randomized controlled trial assessing the impact of a multimodal approach on colorectal cancer screening participation rates in a Federally Qualified Health Center. The trial will test serial text message reminders and opt-out mailed fecal immunochemistry test (FIT) home kits against a simple reminder text message control. Patients aged 50-74 years, who are registered at a Family Practice and Counselling Network (FPCN) clinic and are overdue for colorectal cancer screening will be recruited. The primary outcome is the rate of FIT kits being returned at 12 weeks.

NCT ID: NCT02662348 Enrolling by invitation - Pancreatic Cancer Clinical Trials

T Cell Mediated Adaptive Therapy for Her2-positive Neoplasms of Digestive System

Start date: February 2016
Phase: Phase 1
Study type: Interventional

This phase I trial is to investigate the safety and the possible side effects of bi-specific antibody armed T-cell therapy when given together with low-dose IL-2 in treating patients with Her2-positive neoplasms of digestive system. Expanded autologues T cells that have been coated with bi-specific antibodies, such as anti-CD3 and anti-human epidermal growth factor receptor 2 (HER2), may stimulate the immune system in different ways and stop tumor cells from growing. Interleukin-2 may stimulate white blood cells to kill tumor cells.

NCT ID: NCT02633098 Recruiting - Colorectal Cancer Clinical Trials

A Safety and Effectiveness Study of Pre-operative Artesunate in Stage II/III Colorectal Cancer

NeoART
Start date: April 26, 2017
Phase: Phase 2
Study type: Interventional

This study evaluates the safety and effectiveness of pre-operative artesunate given orally once a day for 14 days prior to surgery in patients with Stage II/III colorectal cancer. Artesunate is an established antimalarial drug with an excellent safety profile, is well tolerated and affordable. A number of laboratory studies and one small pilot clinical study in patients with colorectal cancer have shown that artesunate can reduce the proliferation and growth of cancer cells. Two hundred patients diagnosed with Stage II/III operable colorectal cancer will be randomly allocated to receive oral artesunate 200mg daily or a matching placebo for 14 days prior to surgery. Patients will be followed up closely for 5 years to see if giving artesunate preoperatively reduces the risk of cancer recurring after surgery.

NCT ID: NCT02208401 Completed - Bowel Cancer Clinical Trials

Randomised Comparison of 2 Cold Snare Polypectomy Techniques

Start date: January 2014
Phase: N/A
Study type: Interventional

Different modalities are employed to remove small colonic polyps which potentially harbour a cancer risk. But, they can all vary in their completeness of removal, safety and the histological quality and the gold standard technique has yet to be defined. A novel suction pseudopolyp technique has been described by Patullo et al and in their prospective study, 126 polyps measuring less than 10mm flat or sessile were removed by this method with 100% complete endoscopic resection and without any immediate or delayed complications. The aim of the investigators study is to compare this technique with the standard cold snare technique. Patients attending for a routine colonoscopy and found to have polyps measuring 37mm in size will be eligible and they will be randomised to the polypectomy technique. Patient demographics and polyp characteristics will be recorded. The primary outcome measured will be the macroscopic resection rate. The secondary outcome measures are abdominal pain, tenderness, bleeding and fever.

NCT ID: NCT01868971 Completed - Colorectal Cancer Clinical Trials

Clinical Study to Establish the Feasibility and Usability of the EndoRingsā„¢

Start date: April 2013
Phase: N/A
Study type: Interventional

The purpose of this prospective clinical study is to establish the feasibility and usability of the ENDORINGSā„¢ when used during standard colonoscopy procedure.