Botulinum Toxin, Rejuvenation, Neck, Therapy Clinical Trial
Official title:
Nefertiti Lift for Neck Rejuvenation: Assessing Efficiency and Re-defining Patient Selection
The purpose of this study is to describe a safe and consistent technique for neck rejuvenation using botulinum toxin. This study will also evaluate the efficiency of the intervention and determine the patients that would benefit most.
The abobotulinumtoxinA will be used for the Nefertiti lift The abobotulinumtoxinA will be
prepared by adding 2.5 cc of normal saline to a 500-unit Dysport© (Ipsen Ltd, Berks, UK)
vial Preinjection frontal, oblique and lateral patient pictures will be taken (at rest and
with contraction)
Injection points:
- A series of 4 injection points 1-2 cm apart on a horizontal line under the mandible
posterior to the hypothetical line were the nasolabial fold meets the mandible
- If present, injection of each platysmal band every 2 cm with 2 to 4 injection points
per band (Injection of platysmal band will be done by holding the band between 2
fingers and injecting intramuscularly) For all injection points 5 units per point of
abobotulinumtoxinA will be used
A maximum of 125 units of abobotulinumtoxinA will be allowed for the global neck treatment
Follow up will be done at 15 days for retouching or for post op pictures if no retouching is
needed. if retouching is needed post injection pictures will be taken 10 days post
retouching
Retouching: each residual platysmal band will be reinjected every 2 cm with 2 to 4 injection
points per band (Injection of platysmal band will be done by holding the band between 2
fingers and injecting intramuscularly) (5 units per point of abobotulinumtoxinA will be
used)
A total of 30 patients will be recruited
;
Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment