Clinical Trial Details
— Status: Completed
Administrative data
| NCT number |
NCT05831852 |
| Other study ID # |
RSPL 2.2 |
| Secondary ID |
|
| Status |
Completed |
| Phase |
|
| First received |
|
| Last updated |
|
| Start date |
May 1, 2023 |
| Est. completion date |
September 1, 2023 |
Study information
| Verified date |
September 2023 |
| Source |
October University for Modern Sciences and Arts |
| Contact |
n/a |
| Is FDA regulated |
No |
| Health authority |
|
| Study type |
Observational
|
Clinical Trial Summary
Borderline personality disorder is a mental illness that severely impacts a person's ability
to regulate their emotions. This loss of emotional control can increase impulsivity, affect
how a person feels about themselves, and negatively impact their relationships with others.
In fact, the societal impact of BPDs might be found in emotional suffering, disability and
economic burden. In addition in BPD, the suicide rate might be as high as 8-10%. the presence
of BPD also interferes with response to treatment of physical and psychiatric comorbidities,
such as migraine, HIV, anxiety disorders and substance use disorders. Furthermore, BPD in
particular, are associated with high rates of unemployment, absences from work and
inefficiency at work, with only 25% of patients suffering from BPD working full time and 40%
receiving disability payments. Accordingly, early detection and management would be of great
societal and economic impact. Our Study aim is to validate the Arabic version of Maclean
Instrument for screening and detection of BPD and and investigate the possible risk factors
associated with that disease
Description:
Borderline personality disorder (BPD) is a mental health problem that affects the way you
feel about yourself and others, the way you think , difficulty in managing behavior and
emotions, self-image issues and a pattern of relationships that are unstable. BPD patients
frequently describe their life as unpredictable and stressful. As stated in the Diagnostic
and Statistical Manual of Mental Disorders (5th ed.), borderline personality disorder (BPD)
is a serious mental illness characterized by a pervasive pattern of instability in
interpersonal relationships, self-image and effect, as well as marked impulsivity. This
condition arises in early adulthood or adolescence, leading to severe functional impairment
and subjective discomfort. Unfortunately, diagnosis and treatment of BPD is often delayed,
leading to a less favorable outcome. This is especially true in patients with early onset
BPD, in whom the detection and subsequent therapeutic intervention on the disorder is usually
further put off. Indeed, in the last two decades, there has been a great sensibilization
towards personality disorder (PD)diagnosis in adolescence, reflected in the significant
increase in empirical studies regarding this matter, and in the legitimization of adolescent
PD diagnosis in psychiatric nomenclature (DSM-5 and ICD-11), as well as in national treatment
guidelines in the UK and Australia. Nonetheless, a recent review by Sharp has stressed how
scientific evidence and national practice guidelines are yet to penetrate routine clinical
care. Indeed, in common clinical practice diagnosis and consequently, treatment of BPD is
usually delayed due to underestimation of symptoms and, often, hesitation to diagnose this
disorder in younger individuals. BPD is progressively considered a life expectancy formative
disorder that exists on a layered continuum of severity. The recent studies for the adults
who have BDP disease couldn't find a pharmacological treatment for them. The symptoms
treatment with pharmacotherapy is not accurate for the treatment of BDP in adults, the
pharmacotherapy should not be used for adolescent BPD. The only study exist is about the
using of omega-3 fatty acids and the increase risk of psychosis. Overall, there is no
pharmacological treatment for the BDP disease for adults, also the risks of iatrogenic and
poly-pharmacy toxicity is high in these young people. The other comorbidities of the disease
are treated from the clinical for adolescents, using the pharmacological therapy when needed.
Our study aim is to validate the Arabic version of Maclean Instrument for screening and
detection of BPD and and investigate the possible risk factors associated that disease thus
decreasing the societal and economic burden of that disease
