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Stress & Social Cognition in BPD (Part 2) — SOKO-2  

Borderline Personality Disorder Clinical Trial

Official title:
"Fight-or-flight" Versus "Tend-and-befriend" Response to Behavioral and Pharmacological Interventions in Patients With Borderline Personality Disorder (Part II)

Clinical Trial Summary

The investigators will examine how a combination of pharmacological mineralocorticoid receptor (MR) stimulation and psychosocial stress will influence prosocial behavior in patients with Borderline Personality Disorder (BPD) compared to healthy controls (HC).

Clinical Trial Description

The investigators will examine whether MR stimulation enhances prosocial behavior in BPD patients under additional psychosocial stress. Participants will be randomly assigned to receive either fludrocortisone as an MR stimulant or placebo. Afterwards, participants will either undergo the stress or placebo condition of the Trier Social Stress Test ((P-)TSST). Subsequently, cognitive and emotional empathy, as well as sharing and punishment behavior will be measured. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05310253
Study type Interventional
Source Charite University, Berlin, Germany
Contact Katja Wingenfeld
Phone 004930450517534
Email katja.wingenfeld@charite.de
Status Recruiting
Phase N/A
Start date February 1, 2022
Completion date December 22, 2023
View Details
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