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NCT04504994 Clinical Trial

Stress & Social Cognition in Borderline Personality Disorder

Borderline Personality Disorder Clinical Trial

— SOKO-1  

Official title:
"Fight-or-flight" Versus "Tend-and-befriend" Response to Behavioral and Pharmacological Interventions in Patients With Borderline Personality Disorder - Part I

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT04504994
Other study ID # WI 3396/12-1
Secondary ID
Status Completed
Phase N/A
First received
Last updated
Start date February 1, 2020
Est. completion date December 1, 2021

Study information
Verified date March 2022
Source Charite University, Berlin, Germany
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

The investigators will examine whether perceived social exclusion provoke a reduction in prosocial behavior in BPD patients.

Description:

The investigators will examine whether perceived social exclusion provoke a reduction in prosocial behavior, such as empathy, in BPD patients and whether this "fight-or-flight" pattern is also seen in other relevant aspects of social behavior, such as sharing and punishment behavior. To induce social exclusion all participants will play cyberball, either the exclusion condition or the (over)inclusion condition before testing

Recruitment information / eligibility
Status Completed
Enrollment 196
Est. completion date December 1, 2021
Est. primary completion date December 1, 2021
Accepts healthy volunteers Accepts Healthy Volunteers
Gender Female
Age group 18 Years to 60 Years
Eligibility Inclusion Criteria: female patients with BPD and healthy control women, matched for age, body mass index, and education Exclusion Criteria: physical illness

Study Design

Related Conditions & MeSH terms

Intervention

Behavioral:
• inclusion condition
cyberball game: ex- versus over-inclusion condition

Locations
Country Name City State
Germany Charite University Berlin

Sponsors (1)
Lead Sponsor Collaborator
Charite University, Berlin, Germany

Country where clinical trial is conducted

Germany, 

Outcome
Type Measure Description Time frame Safety issue
Other punishment behavior: number of accepted offers from co-player Computer game 15 minutes after cyberball
Primary empathy Multifaceted Empathy Test 30 minutes after cyberball
Secondary sharing behavior: amount of monetary units (max 30) shared with co-player Computer game directly after cyberball
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