Borderline Personality Disorder Clinical Trial
Official title:
Predictors of Clinical Course and Treatment Response in Patients Having Received Dialectical Behaviour Therapy Delivered by Clinical Units in the Norwegian Network for Clinical Evaluation and Quality in DBT Programmes
The project is a collaboration between The National Centre for Suicide Research and Prevention (NSSF) and clinical units with Dialectical Behaviour Therapy (DBT) programmes. A methodological and technological platform has been established that enables clinicians to deliver high quality treatments over extended periods of time, to evaluate their own performance and productivity and to report it in a uniform and systematic way that will enable comparison across clinical settings and programmes. The collected data constitute the basis for conducting the clinical study with the overall aim to study predictors of the clinical course and treatment response in patients admitted to DBT programmes in Norway.
Status | Recruiting |
Enrollment | 250 |
Est. completion date | December 31, 2023 |
Est. primary completion date | December 31, 2023 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 12 Years to 70 Years |
Eligibility | Inclusion Criteria: - History of repeated deliberate self harm - Satisfies criteria of Diagnostic and Statistical Manual (DSM-IV) Borderline Personality Disorder as measured by Structured Clinical Interview for the DSM (SCID-II) in addition to the self-destructive criterion. Exclusion Criteria: - Psychotic disorders - Anorexia Nervosa - Substance dependence disorder - Mental retardation (IQ less than 70) - Asperger syndrome/autism |
Country | Name | City | State |
---|---|---|---|
Norway | Moss DPS/Østfold sykehus HF | Moss | |
Norway | Søndre Oslo DPS/Oslo Universitetssykehus HF | Oslo | |
Norway | Psykiatrisk senter ytre Helgeland/Helgelandssykehuset HF | Sandnessjøen | |
Norway | Bjerketun behandlingshjem/Vestreviken HF | Sandvika | |
Norway | BUP Lian/St Olavs Hospital HF | Trondheim |
Lead Sponsor | Collaborator |
---|---|
Oslo University Hospital | Nordlandssykehuset HF, St. Olavs Hospital, Sykehuset Ostfold, University of Oslo, Vestre Viken Hospital Trust |
Norway,
Linehan, M.M. (1993a). Cognitive-behavioral treatment of borderline personality disorder. New York: Guilford Press
Linehan, M.M. (1993b). Skills training manual for treating borderline personality disorder. New York: Guilford Press
Miller, A.L., Rathus J.H., Linehan, M.M. (2007). Dialectical behavioral therapy with suicidal adolescents. New York: Guilford Press
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Self-harm behaviour | Number of self-harm episodes (split on suicide attempts and non-suicidal self-harm) | 4 weeks | |
Primary | Suicidal Ideation (adolescents) | Suicidal Ideation Questionnaire (SIQ-Jr). Min=0, Max=90. Higher scores indicate worse outcome | 2 weeks | |
Primary | Depressive symptoms | MADRS (Montgomery Asberg Depression Rating Scale).Min=0, Max=60. Higher scores indicate worse outcome | 1 week | |
Primary | Suicidal Ideation (adults) | Beck Scale for Suicidal Ideation (BSS). MIn=0, Max=38. Higher scores indicate worse outcome | 4 weeks | |
Primary | Depressive symptoms (adolescents) | Moods and Feelings Questionnaire (MFQ). Min=0, Max=26. Higher scores indicate worse outcome | 1 week | |
Primary | Depressive symptoms (adults) | Beck Depression Inventory (BDI). Min=0, Max=63. Higher scores indicate worse outcome | 1 week | |
Secondary | Borderline Symptoms | Borderline Symptom List (BSL-23). Min=0, Max=92. Higher scores indicate more symptoms. | 1 week | |
Secondary | Hopelessness | Beck Hopelessness Scale (BHS). Min=0, Max=20. Higher scores indicate more hopelessness. | 1 week |
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