Borderline Personality Disorder Clinical Trial
Official title:
Mentalization-Based Treatment in Groups for Adolescents With Borderline Personality Disorder (BPD) or Subthreshold BPD Versus Treatment As Usual - the M-GAB Randomized Controlled Trial
Background: Although it is now possible to diagnose Borderline Personality Disorder (BPD) in
adolescents younger than 18 years according to the Diagnostic and Statistical Manual of
Mental Disorders, 5th edition (DSM-V), and studies indicates that BPD can be reliably
diagnosed in adolescence, only a few evidence based treatment programmes for adolescent BPD
exists. Mentalization-based treatment (MBT), including group psychotherapy, has repeatedly
shown to be effective in treating adult BPD, but in the case of adolescents, only individual
MBT have been tested and found to be effective.
Aims/hypotheses: We will test whether group based MBT (MBT-G), including an introductory
programme for patients (MBT-I) and their parents (MBT-P) is more effective than Treatment As
Usual (TAU) in treating adolescents with BPD or subthreshold BPD.
Methods/Design: 112 patients referred to child and adolescent psychiatric clinics in Region
Zealand will be randomized to either MBT or TAU. Inclusion criteria: Meeting DSM-V
BPD-criteria at the threshold (five criteria) or sub threshold level (4 criteria). Follow-up
will be at three and 12 months.
Discussion: Early intervention is especially important in relation to personality
psychopathology and has long-term benefits for patients, their families and society. In
addition to being cost effective, using the group modality in the treatment of BPD may have
several advantages. This is the first Randomized Controlled Trial (RCT) to test the
effectiveness of MBT in groups for adolescents.
n/a
Status | Clinical Trial | Phase | |
---|---|---|---|
Recruiting |
NCT04856449 -
DBT Skills Plus EMDR for BPD and Trauma
|
N/A | |
Active, not recruiting |
NCT04587518 -
Five Factor Model Treatment for Borderline Personality Disorder
|
N/A | |
Recruiting |
NCT05651295 -
A Precision Medicine Approach to Target Engagement for Emotion Regulation
|
N/A | |
Completed |
NCT03677037 -
The Short-Term MBT Project
|
Phase 3 | |
Not yet recruiting |
NCT05989529 -
Delving Into Borderline Personality Disorder Clinical Trial Experiences
|
||
Completed |
NCT02518906 -
Evaluation of AIT Study
|
N/A | |
Recruiting |
NCT04296604 -
Transcranial Direct Current Stimulation (tDCS) Neuromodulation of Executive Function Across Neuropsychiatric Populations
|
N/A | |
Completed |
NCT02108990 -
Acetaminophen and Social Processes
|
Phase 2 | |
Terminated |
NCT02149823 -
Examining Dose-Related Effects of Oxytocin on Social Cognition Across Populations
|
Phase 1 | |
Not yet recruiting |
NCT01683136 -
Evaluation of the HBDL Coil Transcranial Magnetic Stimulation (TMS) Device - Feasibility Study for the Treatment of Borderline Personality Disorder
|
N/A | |
Completed |
NCT01635556 -
Evaluation of a Modified Dialectical Behavior Therapy Program
|
N/A | |
Completed |
NCT02988037 -
Adapted Dialectical Behaviour Therapy for Adolescents With Deliberate Self-Harm: A Pre-post Observational Study
|
N/A | |
Completed |
NCT02397031 -
Mindfulness and Interpersonal Effectiveness Skills in Borderline Personality Disorder
|
N/A | |
Terminated |
NCT01212588 -
Preliminary Trial of the Effect of Glucocorticoid Receptor Antagonist on Borderline Personality Disorder (BPD)
|
Phase 2 | |
Terminated |
NCT01103180 -
Selective Serotonin Reuptake Inhibitors (SSRIs) in Borderline Personality Disorder
|
Phase 2 | |
Terminated |
NCT00539188 -
N-Acetylcysteine in Adjunct to DBT for the Treatment of Self-Injurious Behavior in BPD
|
Phase 2 | |
Recruiting |
NCT05398627 -
Neurofeedback for Borderline Personality Disorder
|
N/A | |
Recruiting |
NCT03994510 -
SHame prOpensity in bOrderline Personality Disorder
|
N/A | |
Recruiting |
NCT06005129 -
Personality Change Study for Borderline Personality Disorder
|
N/A | |
Recruiting |
NCT06406972 -
Brief Admission by Self-referral for Individuals With Self-harm: Effects on Compulsory Care
|