Effects of Comorbid Personality Disorder on the Treatment of Bipolar I Disorder

Borderline Personality Disorder Clinical Trial

Official title:

Treatment of Primary Mood Disorders in the Comorbidly Ill

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT00178061
• Other study ID #: 970843-0109
• Secondary ID: 970843-0109
• Status: Completed
• Phase: Phase 4
• First received: September 13, 2005
• Last updated: June 21, 2013
• Start date: August 1997
• Est. completion date: August 2002

Study information

• Verified date: June 2013
• Source: University of Pittsburgh
• Contact: n/a
• Is FDA regulated: No
• Health authority: United States: Federal Government
• Study type: Interventional

Clinical Trial Summary

This study will examine the impact of comorbid personality disorder on the outcome of treatment among patients with bipolar I disorder.

Description:

The major aim of this proposal is to examine the impact of comorbid personality disorder on the outcome of treatment among patients with bipolar I disorder.

The specific aims are to create a research and supervisory team and to identify potential moderators of treatment response and mediators of outcome over the course of treatment.

Members of the team will meet weekly to begin a treatment development process for enhancing Interpersonal Social Rhythm Therapy (IPSRT) for these patients. Additional assessment measures will be utilized to examine the proposed mediators and moderators of treatment.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 13
• Est. completion date: August 2002
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 18 Years to 60 Years

Eligibility

Inclusion Criteria:

• Bipolar I Disorder with Comorbid Borderline Personality Disorder, currently manic or depressed

Exclusion Criteria:

• Unstable Medical illness

Study Design

Allocation: Non-Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

• Bipolar I Disorder
• Borderline Personality Disorder
• Disease
• Personality Disorders

Intervention

Behavioral:
• Interpersonal Social Rhythm Therapy (IPSRT)

Locations

Country	Name	City	State
United States	Western Psychiatric Institute and Clinic	Pittsburgh	Pennsylvania

Sponsors (1)

Lead Sponsor	Collaborator
University of Pittsburgh

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Hamilton Rating Scale for Depression (HRSD-25)
Secondary	Raskin Severity of Depression and Mania Scales