Cognitive Therapy Versus Supportive Therapy in Borderline Personality Disorder

Borderline Personality Disorder Clinical Trial

Official title:

Cognitive Therapy Versus Supportive Therapy in Borderline Personality Disorder

Clinical Trial Details — Status: Active, not recruiting

Administrative data

• NCT number: NCT00131781
• Other study ID #: 2000.230
• Status: Active, not recruiting
• Phase: N/A
• First received: August 18, 2005
• Last updated: April 26, 2007
• Start date: March 2001

Study information

• Verified date: April 2007
• Source: Hospices Civils de Lyon
• Contact: n/a
• Is FDA regulated: No
• Health authority: France: Ministry of Health
• Study type: Interventional

Clinical Trial Summary

This is a randomised trial comparing cognitive therapy and supportive therapy administered along one year in borderline personality disorder. The follow-up is one year after treatments end.

The therapists were the same in the two groups. Patients received one session a week during six months and one session every two weeks during the next six months

Description:

• Cognitive Therapy

• Structured session

• Conceptualization of the case with the patient

• Cognitive methods

• Guided discovery of the schemas

• Work on life-scenarios

• From scenarios to schemas

• Empathic confrontation to the schemas

• Building new schemas (Core belief work-sheet)

• Affective methods: role playing

• Interpersonal methods: counter transference issues

• Behavioral experiment

• Problem solving

• Consolidation methods

• Patients and therapists had manuals

• Supportive Therapy

• Therapist: active listening (face to face)

• Empathy

• Unconditional positive regard

• Reformulation and clarification

• Reflection of the patient’s feelings

• Reassurance

• Therapist emphasizes the importance to ventilate problems

• Therapist answers some factual questions

• Therapist politely ignore or refuse requests for advice and directive attitudes

• Therapist demonstrates warmth and genuineness

• Patients and therapists had manuals

Recruitment information / eligibility

• Status: Active, not recruiting
• Enrollment: 70
• Gender: Both
• Age group: 18 Years to 65 Years

Eligibility

Inclusion Criteria:

• DSM-4 DIBR >=8 (Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Diagnostic inventory for borderline-revised)

Study Design

Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Single Blind

Related Conditions & MeSH terms

• Borderline Personality Disorder
• Personality Disorders

Intervention

Behavioral:
• Cognitive Therapy

• Supportive Therapy

Locations

Country	Name	City	State
France	Hopital Pierre Wertheimer	Bron

Sponsors (1)

Lead Sponsor	Collaborator
Hospices Civils de Lyon

Country where clinical trial is conducted

France, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Clinical Global Impression (CGI): Improvement (1-7): score 3 ( a little better) associated with a hopelessness scale score < 8 (this means that the suicide risk is low)
Secondary	CGI severity and improvement
Secondary	Hamilton depression
Secondary	Beck Depression Inventory
Secondary	Hopelessness
Secondary	Young: Schema Questionnaire II
Secondary	Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition Personality Disorders Personality Questionnaire (SCID II PQ)
Secondary	Minnesota Multiphasic Personality Inventory (MMPI) (minimult)
Secondary	Eysenck: impulsivity scale
Secondary	Checklist: impulsive risky behaviors
Secondary	Quality of life
Secondary	Handicap (Sheehan)
Secondary	Time: Pre test, six months, post test and one year post treatment follow-up
Secondary	Therapeutic relationship evaluation scale (patients and therapists)