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Bone Turnover Rate Disorder clinical trials

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NCT ID: NCT05880914 Recruiting - Clinical trials for Chronic Kidney Diseases

Precision Medicine Approaches to Renal Osteodystrophy

PMaROD
Start date: December 21, 2022
Phase: Early Phase 1
Study type: Interventional

Treatment of renal osteodystrophy is impeded by the lack of practical and accurate tools to determine underlying bone turnover. Gold standard bone biopsy is not practical in the clinic for the vast majority of kidney disease patients and parathyroid hormone and bone alkaline phosphatase have insufficient accuracy for turnover type to safely and confidently guide treatment of renal osteodystrophy. In the present investigation, the investigators will study a microRNA approach as a novel non-invasive biomarker of turnover for renal osteodystrophy.

NCT ID: NCT05310760 Completed - Clinical trials for Bone Turnover Rate Disorder

Effectiveness of Vitamin C Supplementation in Treatment of Rickets

Start date: March 1, 2022
Phase: Phase 2/Phase 3
Study type: Interventional

Effectiveness of therapeutic dose of vitamin C in infants and children with nutritional rickets as an adjuvant therapy with vitamin D and calcium The study is two armed Randomized Control Trial, to validate the role of Vit C supplementation on bone turnover infants and children with nutritional rickets.

NCT ID: NCT04814316 Completed - Clinical trials for Calcium Metabolism Disorders

Effects of Lansoprazole on Bone Turnover Markers

Start date: December 2, 2019
Phase:
Study type: Observational

Use of proton pump inhibitors (PPI) has increased in recent years. There are concerns that PPIs have possible negative effects on bone metabolism. It has been suggested that PPIs may reduce the absorption of calcium from the small intestine and lead to bone resorption by affecting osteoclastic activity. In this study, it is planned to investigate the effects of lansoprazole, a proton pump inhibitor, on bone turnover markers in pediatric patients with gastroesophageal reflux or gastroesophageal reflux disease.

NCT ID: NCT03618394 Completed - Clinical trials for Bone Turnover Rate Disorder

Bone Turnover and Parenteral Nutrition

Start date: April 1, 2015
Phase:
Study type: Observational

Evaluation of changes in biochemical markers of bone metabolism. Fat profile. Evaluation of the overall body development. Assessment of parenteral nutrition protocols.