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Bone Tumor clinical trials

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NCT ID: NCT03389724 Completed - Cardiotoxicity Clinical Trials

Prevention of Chemotherapy Induced Cardiotoxicity in Children With Bone Tumors and Acute Myeloid Leukemia

Start date: November 14, 2017
Phase: Phase 3
Study type: Interventional

Prevention and early detection of chemotherapy-induced cardiotoxicity in children with bone tumors and Acute Myeloid Leukemia by giving capoten

NCT ID: NCT02862288 Completed - Bone Tumor Clinical Trials

Preliminary Study of Microwave Tumoral Ablation Performances for the Treatment of Pulmonary, Renal and Bone Neoplasia.

TherMO
Start date: September 2012
Phase: Phase 1/Phase 2
Study type: Interventional

The aims of this work were to assess the feasibility, efficacy, short-term outcome and safety of microwave ablation in the treatment of malignant bone, lung and renal tumors.

NCT ID: NCT02398058 Completed - Soft Tissue Sarcoma Clinical Trials

Trabectedin Plus Olaparib in Metastatic or Advanced Sarcomas (TOMAS)

TOMAS
Start date: July 20, 2014
Phase: Phase 1
Study type: Interventional

This is a Phase 1b, multi-site, open-label, non-randomized clinical trial evaluating the safety, tolerability, and pharmacokinetics of escalating doses of olaparib and trabectedin in patients with unresectable advanced/metastatic sarcomas. Patients will continue to be treated on this combination regimen in the absence of disease progression, intolerable toxicity or patient's decision.

NCT ID: NCT01679691 Withdrawn - Bone Tumor Clinical Trials

The Epidural Anesthesia on the Intra-operative and Post-operative Amount of Bleeding Post Lower Limb Salvage Surgery

Start date: September 2011
Phase: N/A
Study type: Interventional

Epidural anesthesia is a very useful tool in lower limb salvage surgery, which helps pain control intra and more importantly post-operative pain. It is a well-known effect of epidural injections to cause a sympathetic stimulation and consequently vasodilatation in the lower limb vessels. Since epidural catheters can cause vasodilatation in lower limb vessels, they can subsequently lead to increased intra and post-operative bleeding from the surgical wound. The study will involve all patients having a bone tumor in the lower limb and subjected to tumor resection and reconstruction by prosthesis. The patient will be randomized according to the administration of epidural anesthesia into two arms, an arm in which epidural anesthesia was employed and another arm in which the patient was subjected only to general anesthesia and the amount of intra and postoperative bleeding will be compared in both arms.

NCT ID: NCT00598741 Completed - Sarcoma Clinical Trials

Dynamic Contrast Enhanced MRI(DCE-MRI)of Bone Tumors

Start date: July 2004
Phase: N/A
Study type: Interventional

The purpose of this study is to see whether fast imaging with MRI and the usual contrast material used for MRI, predicts which patients will do well with treatment. Some studies suggest that MRIs done right before surgery may be able to tell how much of the cancer was killed by the chemotherapy. This study will see if this is true in patients with osteogenic sarcoma (OS) and Ewing's sarcoma (ES). This study will also see if MRIs done early in treatment can tell if the chemotherapy is working.