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Bone Substitute clinical trials

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NCT ID: NCT06247098 Not yet recruiting - Dental Implant Clinical Trials

Evaluation of Sinus Augmentation Bone Healing Using Autograft and Xenograft Compared to Xenograft Alone

Start date: March 2024
Phase: N/A
Study type: Interventional

To evaluate bone healing at 4 months after lateral sinus augmentation with a 4:1 ratio of autologous bone and xenograft or xenograft alone. A radiographic volumetric, histomorphometric, and histologic analysis.

NCT ID: NCT06044246 Not yet recruiting - Dental Implantation Clinical Trials

Influence of Human Platelet Derivatives on Dental Implant

Start date: June 20, 2024
Phase: N/A
Study type: Interventional

The goal of this randomized controlled trial is to evaluate the benefit of PRF membrane on bone around dental implant in patients who need treatment with dental implant. Aims of the study: - To study the effect of PRF membrane (with or without bone substitute on increasing bone dimension around dental implant. - To investigate the effects of compositions of PRF (platelets count, WBC count) on bone healing.

NCT ID: NCT05938907 Recruiting - Bone Substitute Clinical Trials

Effect of Concentrated Growth Factors on Healing of Apicomarginal Defects: a Prospective Study

Start date: June 15, 2023
Phase: N/A
Study type: Interventional

The persistent and chronic apical periodontitis has caused great difficulties for clinical physicians. Ensuring rapid and successful healing of the extensively damaged periapical region is a pressing issue that needs to be addressed. The treatment options include traditional apical surgery, simultaneous placement of bone powder and membrane after apical surgery, and simultaneous placement of sticky bone (bone powder mixed with concentrated growth factors gel) and membrane. However, high-quality evidence regarding these various treatment options is scarce. The purpose of this study is to compare the advantages and disadvantages of each treatment option, in order to guide clinical physicians in the application of apical surgery.

NCT ID: NCT05377710 Not yet recruiting - Bone Substitute Clinical Trials

Evaluation of the Safety and Performance of Glycobone in Sinus Lift

SL
Start date: May 16, 2022
Phase: N/A
Study type: Interventional

Multicentre, interventional, longitudinal, open-label study conducted in France, evaluating the clinical performance and safety of Glycobone® as a bone filling material in the context of a lateral approach sinus lift on 40 patients with dental implant placement. Implant placement took place 6 months after bone filling.

NCT ID: NCT02120053 Active, not recruiting - Alveolar Bone Loss Clinical Trials

Interest of Bone Substitute Material in Immediate Complete Denture

PANORAMIX
Start date: October 2013
Phase: Phase 2/Phase 3
Study type: Interventional

More than 2 million French people suffer from the widespread disability of edentulism, with large consequences on function, nutrition, aesthetics and well-being. Complete denture is a common therapeutic strategy. The immediate complete denture technique consists in placing the denture in the same clinical session as last anterior teeth extractions. With this technique, aesthetic and function are immediately reintroduced and the patient is never left toothless or without any denture. After teeth extractions, alveolar healing process leads to ridge resorption with bone volume modifications and reduction in height and width. However ridge bone volume is an essential factor in removable denture stability. With implantology as an alternative prosthetic strategy, ridge volume is also a most important factor to place dental implants in a situation close to previous dental roots position. In order to preserve bone volume, a current alternative strategy proposes to place bone substitute materials in tooth sockets after extraction. This strategy was never evaluated with the immediate complete denture technique. Hypothesis: A new strategy associating immediate complete denture and bone substitute material is more effective than conventional immediate complete denture in a bone preservation perspective.