Alveolar Ridge Augmentation Following Tooth Extraction Using Bovine Xenograft With Platelet Rich Fibrin Membrane

Bone Regeneration Clinical Trial

Official title:

Alveolar Ridge Augmentation Following Tooth Extraction Using Bovine Xenograft With Platelet Rich Fibrin Membrane

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05791123
• Other study ID #: REC-FDBSU/05012023-03/ER
• Status: Completed
• Phase: N/A
• Start date: July 15, 2018
• Est. completion date: March 5, 2023

Study information

• Verified date: March 2023
• Source: Future University in Egypt
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

fourteen patients requiring extraction of one posterior tooth with lost buccal bone (>50%) confirmed preoperatively by Cone-beam computed tomography (CBCT) scans. Extraction sockets were filled with minced PRF clots mixed with the bovine xenograft and covered by PRF membranes to seal the extraction sockets. (CBCT) scans, performed before tooth extraction and after 6 months, were used to assess vertical and horizontal bone changes.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 14
• Est. completion date: March 5, 2023
• Est. primary completion date: February 20, 2023
• Accepts healthy volunteers: No
• Gender: All
• Age group: 20 Years to 60 Years

Eligibility

Inclusion Criteria:

• Patients required implant treatment after tooth extraction

• Age group ranged from 20-60 years old.

• Patients could undergo the treatment under local anesthesia.

• Loss of buccal bone (>50%) confirmed by preoperative cone beam computed tomography (CBCT).

• Presence of other socket walls; mesial, distal and lingual walls.

• Tooth needed to be extracted in upper or lower posterior regions

Exclusion Criteria:

• Uncontrolled diabetic diseases.

• Uncontrolled hypertension, or hepatic and renal disorders.

• Any systemic diseases associated with bone metabolism.

Related Conditions & MeSH terms

• Bone Regeneration

Intervention

Procedure:
• a bone graft mixed with PRF & covered by PRF membrane in fresh extraction socket
Extraction sockets were filled with minced PRF clots mixed with the bovine xenograft and covered by PRF membranes to seal the extraction sockets.

Locations

Country	Name	City	State
Egypt	Future University in Egypt	Cairo

Sponsors (1)

Lead Sponsor	Collaborator
Future University in Egypt

Country where clinical trial is conducted

Egypt, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	the change in alveolar bone width and height in mm using CBCT scans.	Cone Beam Computed Tomography were taken for each patients before tooth extraction and after 6 months, which were used to assess alveolar ridge changes in width and length in mm.	6 months