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NCT05791123 Clinical Trial

Alveolar Ridge Augmentation Following Tooth Extraction Using Bovine Xenograft With Platelet Rich Fibrin Membrane

Bone Regeneration Clinical Trial

Official title:
Alveolar Ridge Augmentation Following Tooth Extraction Using Bovine Xenograft With Platelet Rich Fibrin Membrane

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT05791123
Other study ID # REC-FDBSU/05012023-03/ER
Secondary ID
Status Completed
Phase N/A
First received
Last updated
Start date July 15, 2018
Est. completion date March 5, 2023

Study information
Verified date March 2023
Source Future University in Egypt
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

fourteen patients requiring extraction of one posterior tooth with lost buccal bone (>50%) confirmed preoperatively by Cone-beam computed tomography (CBCT) scans. Extraction sockets were filled with minced PRF clots mixed with the bovine xenograft and covered by PRF membranes to seal the extraction sockets. (CBCT) scans, performed before tooth extraction and after 6 months, were used to assess vertical and horizontal bone changes.

Recruitment information / eligibility
Status Completed
Enrollment 14
Est. completion date March 5, 2023
Est. primary completion date February 20, 2023
Accepts healthy volunteers No
Gender All
Age group 20 Years to 60 Years
Eligibility Inclusion Criteria: - Patients required implant treatment after tooth extraction - Age group ranged from 20-60 years old. - Patients could undergo the treatment under local anesthesia. - Loss of buccal bone (>50%) confirmed by preoperative cone beam computed tomography (CBCT). - Presence of other socket walls; mesial, distal and lingual walls. - Tooth needed to be extracted in upper or lower posterior regions Exclusion Criteria: - Uncontrolled diabetic diseases. - Uncontrolled hypertension, or hepatic and renal disorders. - Any systemic diseases associated with bone metabolism.

Study Design

Related Conditions & MeSH terms

Intervention

Procedure:
• a bone graft mixed with PRF & covered by PRF membrane in fresh extraction socket
Extraction sockets were filled with minced PRF clots mixed with the bovine xenograft and covered by PRF membranes to seal the extraction sockets.

Locations
Country Name City State
Egypt Future University in Egypt Cairo

Sponsors (1)
Lead Sponsor Collaborator
Future University in Egypt

Country where clinical trial is conducted

Egypt, 

Outcome
Type Measure Description Time frame Safety issue
Primary the change in alveolar bone width and height in mm using CBCT scans. Cone Beam Computed Tomography were taken for each patients before tooth extraction and after 6 months, which were used to assess alveolar ridge changes in width and length in mm. 6 months
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