Adherence, Medication Clinical Trial
Official title:
Pilot Study on the ADherence to Oral Antibiotics in Patients With BONE and Joint Infections (ADABONE)
Bone and joint infection (BJI) are bacterial infections that can occur after surgery
(nosocomial infections) or de novo. They constitute a public health problem in Western
Countries . These infections are often difficult to treat, with a high rate of
re-hospitalizations (19.5%) caused by relapses or recurrences. The treatment of Bone and
joint infection can be surgical and / or pharmacological . Drug treatment is based on the use
of parenteral and / or oral antibiotics. It is a curative therapy in most cases, with a
prolonged duration ranging from 6 weeks to several months depending on the lesions .
Medication adherence, is a patients' behavior defined as drug intake with optimal attendance
and regularity, as prescribed and explained by the physician. It is a key factor in the
success of any drug therapy, as drugs don't work in patients who don't take them..
To the knowledge of investigators, there are no published data on the adherence to antibiotic
therapy in patients treated for Bone and joint infection. In addition to its prolonged
duration, the antibiotic treatment of the Osteoarticular Infections may require several daily
drug intakes and may be responsible for severe adverse effects, these three factors being
known to adversely affect adherence.
Prevalence, adherence patterns over time and determinants of adherence in this patient
population are not known. Currently, drug adherence is not routinely evaluated and is not
considered in the treatment of Bone and joint infection in the Regional Center for Complex
Bone and joint infection of the investigators.
A specific study evaluating adherence to antibiotic therapy in patients treated for Bone and
joint infection appears to be justified.
n/a
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT05546931 -
Mobile Health Program for Rural Hypertension
|
N/A | |
| Recruiting |
NCT04316715 -
Life-Steps Counseling to Enhance Adherence and Engagement in PrEP Care
|
N/A | |
| Active, not recruiting |
NCT04602468 -
Real World Clinical Outcomes With Novel Modulator Therapy Combinations in People With CF (RECOVER)
|
Phase 4 | |
| Active, not recruiting |
NCT04588883 -
Strengthening Families Living With HIV in Kenya
|
N/A | |
| Enrolling by invitation |
NCT04676204 -
Relationship Between Oral DMT Burden and Adherence in MS
|
||
| Not yet recruiting |
NCT03807388 -
ReMindCare App for Patients From First Episode of Psychosis Unit.
|
N/A | |
| Completed |
NCT05168449 -
The Impact of Pharmacist-led Mobile Application on Adherence in Chronic Kidney Disease Patients
|
N/A | |
| Active, not recruiting |
NCT04612088 -
Intervention for Multivitamin Adherence on Bariatric Patients
|
N/A | |
| Completed |
NCT03958331 -
Behavioral Economics and Adherence in Teens (BEAT!)
|
N/A | |
| Completed |
NCT05233644 -
Medication Adherence in Heart Failure After Hospitalisation
|
||
| Completed |
NCT03837496 -
Small-group, Virtual Program for Improving Symptoms and Distress Related to Hormonal Therapy for Breast Cancer Survivors
|
N/A | |
| Recruiting |
NCT03683966 -
MigALastat Therapy Adherence Among FABRY Patients: A Prospective Multicentral Observational Study
|
||
| Withdrawn |
NCT04754867 -
Pre-Test of For the Future Self and Smoking Cessation
|
N/A | |
| Recruiting |
NCT05996094 -
Antiretroviral Adherence and Drug-level Monitoring
|
||
| Not yet recruiting |
NCT06056037 -
Making ART Work Among Brazilian Youth
|
N/A | |
| Completed |
NCT03658252 -
Efficacy of Targeted Intervention for Topical Steroid Phobia.
|
N/A | |
| Completed |
NCT03651596 -
Leveraging mHealth Messaging to Promote Adherence in Teens With CKD
|
N/A | |
| Completed |
NCT03842436 -
Feasibility and Acceptability of Digital Pills to Monitor PrEP Adherence in MSM With Substance Use
|
Phase 4 | |
| Completed |
NCT03081559 -
Improving Engagement in HIV Care for High-risk Women
|
N/A | |
| Recruiting |
NCT05515497 -
BMT4me: Post-HSCT Medication Adherence mHealth App
|
N/A |