The Effects of Rhus Coriaria L. on Body Weight

Body Weight Clinical Trial

— SomaghWeight  

Official title:

The Effects of Rhus Coriaria L. (Rhus or Somagh) on Body Weight

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02754089
• Other study ID #: CT-92-5581
• Status: Completed
• Phase: N/A
• Start date: May 2016
• Est. completion date: September 2016

Study information

• Verified date: September 2016
• Source: Shiraz University of Medical Sciences
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The aim of this study is to evaluate the effects of Rhus coriaria L. (Rhus) commonly known as "Somagh" on body weight.

Description:

Rhus coriaria L.(Rhus) is a well-known spice widely consumed in the world which has also been utilized extensively for medicinal purposes. The antioxidant components of this plant made it a favorable target for laboratory and animal studies in different conditions such as oxidative stress cytotoxicity, diabetes and hyperlipidemia. Rhus (Somagh) is found in temperate and tropical regions worldwide, often growing in areas of marginal agricultural capacity. Rhus is used as an herbal remedy in traditional medicine because of its assumed analgesic, antidiarrheic, antiseptic, anorexic and antihyperglycemic properties. The fruits of Rhus contain flavonols, phenolic acids, hydrolysable tannins, anthocyans and organic acids such as malice, citric and tartaric acids. Some studies have shown that polyphenols could have beneficial effects on cardiovascular disease and cancer and could be regarded as bioactive compounds with a high potential health-promoting capacity. Phenolic compounds inhibit lipid peroxidation, scavenge the superoxide anion and hydroxyl radical, and enhance the activities of detoxifying enzymes.

The aim of this study is to evaluate the effects of Rhus coriaria L. (Rhus) commonly known as Somagh on body weight.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 50
• Est. completion date: September 2016
• Est. primary completion date: September 2016
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 60 Years

Eligibility

Inclusion Criteria:

• Body mass index (BMI) >= 25 kg/m2

Exclusion Criteria:

• Diabetes mellitus

• Hypo. or hyperthyroidism

• Any systemic illnesses e.g. liver cirrhosis, acute or chronic renal failure, heart failure

• Use of drugs: Weight lowering agents, glucocorticoids, Oral contraceptive pills.

• Pregnancy

• History of allergic reaction to Somagh

Related Conditions & MeSH terms

• Body Weight

Intervention

Drug:
• Rhus Coriaria L.(Rhus)
500 mg twice daily after meals for 6 weeks
• Placebo
500 mg twice daily after meals for 6 weeks

Locations

Country	Name	City	State
Iran, Islamic Republic of	Shahid Motahhari Clinic, Shiraz University of Medical Sciences	Shiraz	Fars

Sponsors (1)

Lead Sponsor	Collaborator
Shiraz University of Medical Sciences

Country where clinical trial is conducted

Iran, Islamic Republic of, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Body Mass Index		6 weeks
Secondary	Waist Circumference (cm)		6 weeks
Secondary	Hip Circumference (cm)		6 weeks
Secondary	Leptin (ng/ml)		6 weeks
Secondary	Insulin (mU/l)		6 weeks
Secondary	Fasting Blood Glucose (mg/dl)		6 weeks
Secondary	Number of patients with adverse event		6 weeks