Effect of Ginseng on Blood Pressure

Blood Pressure Clinical Trial

Official title:

Effect of Ginseng on Blood Pressure: A Systematic Review and Meta-Analysis of Controlled Trials

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01913210
• Other study ID #: MetaBPG
• Status: Completed
• Phase: N/A
• First received: July 29, 2013
• Last updated: March 2, 2016
• Start date: April 2013
• Est. completion date: January 2016

Study information

• Verified date: March 2016
• Source: St. Michael's Hospital, Toronto
• Contact: n/a
• Is FDA regulated: No
• Health authority: Canada: St. Michael's Hospital (Dr. Vladmir Vuksan)
• Study type: Observational

Clinical Trial Summary

To determine the effect of ginseng on blood pressure control.

Description:

The effect of ginseng on blood pressure control is controversial, originating from an early 1970s observational study, suggesting that ginseng may adversely effect blood pressure. Despite these early findings, extensive research has since suggested that ginseng may have a positive effect on blood pressure. The current study will help clarify present uncertainty on the effect of ginseng on blood pressure control.

This systematic review and meta-analysis will follow The Cochrane Handbook for Systematic Reviews of Interventions. MEDLINE, EMBASE, CINAHL and The Cochrane Central Register of Controlled Trials will be searched using appropriate search terms. Intervention trials that investigate the effect of ginseng on blood pressure in humans will be included.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 500
• Est. completion date: January 2016
• Est. primary completion date: May 2013
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: N/A and older

Eligibility

Inclusion Criteria:

• clinical trials in humans

• randomized treatment allocation

• = 1 month

• suitable control

• viable endpoint data

Exclusion Criteria:

• non-human studies

• non-randomized treatment allocation

• < 1 month

• lack of a suitable control

• no viable endpoint data

• trials where ginseng is part of a multi-herbal treatment

Study Design

Time Perspective: Prospective

Related Conditions & MeSH terms

• Blood Pressure

Intervention

Dietary Supplement:
• Ginseng

Locations

Country	Name	City	State
Canada	The Toronto 3D Knowledge Synthesis and Clinical Trials Unit, Clinical Nutrition and Risk Factor Modification Centre	Toronto	Ontario

Sponsors (1)

Lead Sponsor	Collaborator
St. Michael's Hospital, Toronto

Country where clinical trial is conducted

Canada, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Systolic Blood Pressure		1 month	No
Secondary	Diastolic Blood Pressure		1 month	No
Secondary	Mean Arterial Pressure		1 month	No