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Blood Loss, Surgical clinical trials

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NCT ID: NCT05273632 Completed - Clinical trials for Blood Loss, Surgical

Comparison Study of Oxytocin Versus Tranexamic Acid and Etamsylaye Versus Placebo(Saline)

Start date: March 20, 2022
Phase: N/A
Study type: Interventional

Comparison Study Between Oxytocin Versus Tranexamic Acid and Ethamsylate Versus Normal Saline as Pre-operative Administration.

NCT ID: NCT05258487 Completed - Clinical trials for Intraoperative Blood Loss

The Utility of the Validated Intraoperative Bleeding Scale in Spine Surgery

Start date: March 1, 2022
Phase:
Study type: Observational

This is a single-center, prospective, observational study that will compare the blood transfusion rate between intraoperative bleeding severity characterized using the Validated Intraoperative Bleeding Scale (VIBe).

NCT ID: NCT05220787 Recruiting - Bleeding Clinical Trials

Extended Cold Stored Apheresis Platelets in Cardiac Surgery Patients

CHASE
Start date: February 21, 2022
Phase: Phase 1/Phase 2
Study type: Interventional

This trial is being performed to evaluate the feasibility of the study protocol and to test the efficacy and safety of platelets stored at cold conditions (1-6°C) in 100% plasma for 10-14 days (CSP) in cardiac surgery patients who are actively bleeding and require platelet transfusion.

NCT ID: NCT05164809 Recruiting - Clinical trials for Blood Loss, Surgical

Effect of Electrosurgery on Blood Loss and Intraoperative Transfusions in Musculoskeletal Tumor Surgery

Start date: October 1, 2021
Phase:
Study type: Observational

Resection of malign musculoskeletal tumors and reconstruction with large tumor prostheses often results in relevant blood loss requiring hemodynamic stabilization and transfusion. The use of novel electrosurgical electrodes is assessed retrospectively regarding the potential to reduce blood loss and the need for transfusions.

NCT ID: NCT05108597 Completed - Clinical trials for Blood Loss, Surgical

Effect of Rectal Misoprostol in Reducing Intra-operative Blood Loss During Myomectomy

Start date: March 4, 2019
Phase: Phase 3
Study type: Interventional

A total of 200 women for elective abdominal myomectomy were randomly allocated into two groups. 100 women in experimental group were administered 400ug Misoprostol (2 tablets of Prosotec®) through the rectal route prior to surgery and 100 were in control group, in which no drug was administered.

NCT ID: NCT05093504 Terminated - Clinical trials for Blood Loss, Surgical

Safe and Timely Antithrombotic Removal - Direct Oral Anticoagulants Apixaban & Rivaroxaban (STAR-D)

STAR-D
Start date: December 27, 2021
Phase: N/A
Study type: Interventional

Prospective, Multicenter, Double-blind, Randomized, Study to Evaluate DrugSorb-ATR Removal of Apixaban and Rivaroxaban to Reduce Likelihood of Serious Bleeding in Patients Undergoing Urgent Cardiothoracic Surgery

NCT ID: NCT05081375 Terminated - Surgical Blood Loss Clinical Trials

Pre-operative Enoxaparin in the Surgical Management of Multi-trauma Patients Undergoing Orthopedic Surgical Procedures

Start date: December 16, 2019
Phase: Phase 4
Study type: Interventional

All trauma patients receive Lovenox or other prophylactic medication to prevent deep vein clots from forming. For the trauma patients with orthopedic injuries requiring surgery there is controversy over safety and efficacy when prophylaxis is started preoperatively vs postoperatively. This study is to evaluate both approaches for safety in terms of bleeding events during and 24 hours after surgery as well as preventing deep vein clot formation. This will be a randomized double blinded study using Lovenox or placebo as the medications given preoperatively. Postoperative Lovenox will be given to both groups per routine regime.

NCT ID: NCT05077124 Recruiting - Clinical trials for Blood Loss, Surgical

Safe and Timely Antithrombotic Removal (STAR) Registry

Start date: September 30, 2021
Phase:
Study type: Observational

This registry will capture real-world clinical use patterns and associated clinical outcomes with the use of CytoSorb for the removal of antithrombotic agents.

NCT ID: NCT05035303 Completed - Clinical trials for Blood Loss, Surgical

Can Trajectory Nor-epinephrine Infiltration Reduce Blood Loss During Percutaneous Nephrolithotomy (PCNL)?

Start date: March 10, 2020
Phase: N/A
Study type: Interventional

during PCNL; A few milliliters of nor-epinephrine is injected into the intended tract after puncture of pelvicalyceal system and before its dilatation compared to injection of saline (placebo). hemoglobin change & blood loss is estimated and will compared.

NCT ID: NCT04976530 Completed - Clinical trials for Blood Loss, Surgical

Safe and Timely Antithrombotic Removal - Ticagrelor (STAR-T)

STAR-T
Start date: August 31, 2021
Phase: N/A
Study type: Interventional

Prospective, multi-center, double-blind, randomized pivotal trial to evaluate the safety and effectiveness of the DrugSorb-ATR system for intraoperative removal of ticagrelor in patients undergoing urgent cardiothoracic (CT) surgery with cardiopulmonary bypass (CPB).